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DRUG:

HLX60

i
Other names: HLX60
Associations
Company:
Fosun Pharma
Drug class:
LRRC32 inhibitor
Related drugs:
Associations
7ms
A Study to Investigate the Safety, Tolerability and Efficacy of HLX60 Combination With HLX10 in Subjects With Advanced or Metastatic Solid Tumors (clinicaltrials.gov)
P1, N=20, Active, not recruiting, Shanghai Henlius Biotech | Recruiting --> Active, not recruiting | Trial completion date: Feb 2025 --> Aug 2025 | Trial primary completion date: Feb 2024 --> Dec 2024
Enrollment closed • Trial completion date • Trial primary completion date • Metastases
|
PD-L1 (Programmed death ligand 1)
|
PD-L1 expression
|
Hetronifly (serplulimab) • HLX60
7ms
A Phase I Study to Investigate the Safety, Tolerability and PK of HLX60 (Anti-GARP Monoclonal Antibody) in Subjects With Solid Tumors or Lymphoma (clinicaltrials.gov)
P1, N=11, Active, not recruiting, Shanghai Henlius Biotech | Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2024 --> Aug 2024
Enrollment closed • Trial primary completion date • Metastases
|
HLX60
over1year
A Study to Investigate the Safety, Tolerability and Efficacy of HLX60 Combination With HLX10 in Subjects With Advanced or Metastatic Solid Tumors (clinicaltrials.gov)
P1, N=20, Recruiting, Shanghai Henlius Biotech | Not yet recruiting --> Recruiting | N=11 --> 20 | Trial completion date: May 2024 --> Feb 2025 | Trial primary completion date: Sep 2023 --> Feb 2024
Enrollment open • Enrollment change • Trial completion date • Trial primary completion date • IO biomarker • Metastases
|
PD-L1 (Programmed death ligand 1) • FOXP3 (Forkhead Box P3)
|
PD-L1 expression
|
Hetronifly (serplulimab) • HLX60
over2years
New P1 trial • IO biomarker
|
PD-L1 (Programmed death ligand 1) • FOXP3 (Forkhead Box P3)
|
PD-L1 expression
|
Hetronifly (serplulimab) • HLX60