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    BIOMARKER:

    HLA-A*30

    i
    Other names: HLA-A, Major Histocompatibility Complex, Class I, A, HLA Class I Histocompatibility Antigen, A Alpha Chain, HLAA, HLA Class I Histocompatibility Antigen, A-1 Alpha Chain, MHC Class I Antigen HLA-A Heavy Chain, Leukocyte Antigen Class I-A, Human Leukocyte Antigen A
    Entrez ID:
    3105
    Related biomarkers:
    Expression
    Mutation
    Others
    11ms
    The role of human leukocyte antigen in HTLV-1 infection and progression to ATLL and HAM/TSP: a systematic review and meta-analysis. (PubMed, Virol J)
    Additionally, our results propound that carriers of HLA-A*28, B*54, C*07, DQB1*03:01, and DRB1*07:01 are at higher risk, and carriers of HLA-A*30, B*37, B*40, B*44, C*08, DQB1*06:02, and DRB1*15:01 are in lower risk of HTLV progression to HAM/TSP. We concluded that the mentioned HLA alleles are potential biomarkers of HTLV infection and its progression to related diseases.
    Clinical • Retrospective data • Review • Journal
    |
    HLA-DRB1 (Major Histocompatibility Complex, Class II, DR Beta 1) • HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ Beta 1) • HLA-B (Major Histocompatibility Complex, Class I, B)
    |
    HLA-A*30
    11ms
    Whole exome-seq and RNA-seq data reveal unique neoantigen profiles in Kenyan breast cancer patients. (PubMed, Front Oncol)
    The unique neoantigen profiles in our patient group highlight the potential of immunotherapy in personalized breast cancer treatment as well as potential biomarkers for prognosis. The unique mutations producing these neoantigens, compared to other populations, provide an opportunity for validation in a much larger sample cohort.
    Journal • BRCA Biomarker • IO biomarker
    |
    TP53 (Tumor protein P53) • BRCA2 (Breast cancer 2, early onset) • RB1 (RB Transcriptional Corepressor 1) • HLA-A (Major Histocompatibility Complex, Class I, A) • MUC16 (Mucin 16, Cell Surface Associated) • HLA-B (Major Histocompatibility Complex, Class I, B) • CDH23 (Cadherin Related 23) • HLA-C (Major Histocompatibility Complex, Class I, C) • MUC17 (Mucin 17)
    |
    HLA-A*02 • HLA-A*30