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    DRUG:

    GT201

    i
    Other names: GT201, Autologous tumor infiltrating lymphocyte injection, GT 201
    Associations

    News

    Trials
    Company:
    Grit Biotechnology
    Drug class:
    Immunostimulant
    Related drugs:
    Associations

    News

    Trials
    5ms
    Autologous Tumor-Infiltrating Lymphocyte Injection(GT201) for Treatment of Patients With Advanced Lung Cancer (clinicaltrials.gov)
    P=N/A, N=16, Recruiting, Grit Biotechnology
    New trial • Metastases
    |
    GT201
    5ms
    Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Squamous Cell Carcinoma (clinicaltrials.gov)
    P=N/A, N=32, Recruiting, Grit Biotechnology | Not yet recruiting --> Recruiting
    Enrollment open • Combination therapy • Metastases
    |
    GT201
    9ms
    Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Squamous Cell Carcinoma (clinicaltrials.gov)
    P=N/A, N=32, Not yet recruiting, Grit Biotechnology | Trial completion date: Jan 2027 --> Apr 2027 | Initiation date: Jan 2024 --> Apr 2024 | Trial primary completion date: Jan 2027 --> Apr 2027
    Trial completion date • Trial initiation date • Trial primary completion date • Combination therapy • Metastases
    |
    GT201
    10ms
    GT201 Injection in Combination With Teraplizumab Injection for Treatment of Patients With Non-small Cell Lung Cancer (clinicaltrials.gov)
    P=N/A, N=20, Recruiting, Grit Biotechnology | Not yet recruiting --> Recruiting
    Enrollment open • Combination therapy
    |
    GT201
    11ms
    Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Squamous Cell Carcinoma (clinicaltrials.gov)
    P=N/A, N=32, Not yet recruiting, Grit Biotechnology | N=20 --> 32
    Enrollment change • Combination therapy • Metastases
    |
    GT201
    12ms
    Clinical Study of GT201 in the Treatment of Advanced Gynecological Tumors (Advanced Cervical Cancer) (clinicaltrials.gov)
    P=N/A, N=26, Recruiting, Grit Biotechnology
    New trial • Metastases
    |
    GT201
    12ms
    Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Squamous Cell Carcinoma (clinicaltrials.gov)
    P=N/A, N=20, Not yet recruiting, Grit Biotechnology
    New trial • Combination therapy • Metastases
    |
    GT201
    1year
    GT201 Injection For The Treatment Of Advanced Solid Tumors (clinicaltrials.gov)
    P1/2, N=18, Recruiting, Grit Biotechnology
    New P1/2 trial • Metastases
    |
    GT201
    1year
    Clinical Study of Autologous Tumor-infiltrating Lymphocyte Injection (GT201) for Advanced Solid Tumors (clinicaltrials.gov)
    P1, N=26, Recruiting, Grit Biotechnology | Phase classification: P1/2 --> P1
    Phase classification • Metastases
    |
    GT201
    over1year
    A Functionally Enhanced Tumor-Infiltrating Lymphocytes Product (GT201) Exhibits Improved Persistence and Anti-Tumor Efficacy with Low IL-2 Dependency (ASGCT 2023)
    Taken together, GT201 demonstrated enhanced persistence and anti-tumor efficacy with low IL-2 dependency in vitro and in vivo. Currently, manufacturing process of GT201 TIL product has been successfully developed (StaViral®), and clinical assessment of GT201 as a next-generation TIL therapy is ongoing in an investigator-initiated trial in China.
    Clinical • Tumor-infiltrating lymphocyte
    |
    IFNG (Interferon, gamma) • IL2 (Interleukin 2)
    |
    IL2-L
    |
    GT201