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    BIOMARKER:

    GPX4 rs4807542

    i
    Other names: GPX4, Glutathione Peroxidase 4, PHGPx, Phospholipid Hydroperoxide Glutathione Peroxidase, Phospholipid Hydroperoxidase, GSHPx-4, GPx-4, MCSP, Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial, Glutathione Peroxidase 4 (Phospholipid Hydroperoxidase), Epididymis Secretory Sperm Binding Protein, Sperm Nucleus Glutathione Peroxidase, SnPHGPx, SnGPx, SMDS, GPX4
    Entrez ID:
    2879
    Related biomarkers:
    Expression
    over2years
    Germline Polymorphisms in Genes Involved in the Antioxidant System Predict the Efficacy of Cetuximab in Metastatic Colorectal Cancer Patients Enrolled in FIRE-3 Trial. (PubMed, Clin Colorectal Cancer)
    TXN2 rs4821494 involved in the antioxidant system may predict the efficacy of cetuximab-based first-line chemotherapy in mCRC, warranting further validation studies.
    Journal
    |
    GPX4 (Glutathione Peroxidase 4)
    |
    GPX4 rs4807542 • TXN2 rs4821494
    |
    Avastin (bevacizumab) • Erbitux (cetuximab) • 5-fluorouracil • irinotecan • leucovorin calcium