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    BIOMARKER:

    GPX2 underexpression

    i
    Other names: GPX2, GSHPX-GI, Glutathione peroxidase 2 (gastrointestinal)
    Entrez ID:
    2877
    over1year
    Evaluation of the Use of Cell Lines in Studies of Selenium-Dependent Glutathione Peroxidase 2 (GPX2) Involvement in Colorectal Cancer. (PubMed, Diseases)
    However, the source normal cells for CRC could be almost any colon cell type, some with very high GPX2 levels. These factors are addressed in this study.
    Preclinical • Journal
    |
    GPX2 (Glutathione peroxidase 2 (gastrointestinal))
    |
    GPX2 underexpression
    3years
    GPX2 is a potential therapeutic target to induce cell apoptosis in lenvatinib against hepatocellular carcinoma. (PubMed, J Adv Res)
    Our findings indicated that GPX2 plays an important role in lenvatinib-induced HCC cell apoptosis, which might serve as a biomarker for instruction of lenvatinib therapy in HCC patients.
    Journal
    |
    GPX2 (Glutathione peroxidase 2 (gastrointestinal))
    |
    GPX2 underexpression
    |
    Lenvima (lenvatinib)