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    GENE:

    GPRIN2 (G Protein Regulated Inducer Of Neurite Outgrowth 2)

    i
    Other names: GPRIN2, G Protein Regulated Inducer Of Neurite Outgrowth 2, KIAA0514, G Protein-Regulated Inducer Of Neurite Outgrowth 2, MGC15171, GRIN2
    Associations

    News

    Trials
    over1year
    Ferredoxin 1: a gatekeeper in halting lung adenocarcinoma progression through activation of the GPRIN2 signaling pathway. (PubMed, J Transl Med)
    Our findings highlight FDX1 as a potential tumor suppressor in LUAD, acting through modulation of the GPRIN2/PI3K signaling pathway. These results suggest FDX1 as a promising therapeutic target for LUAD treatment, warranting further investigation into its clinical relevance.
    Journal
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    FDX1 (Ferredoxin 1) • GPRIN2 (G Protein Regulated Inducer Of Neurite Outgrowth 2)
    over2years
    Identification of molecular biomarkers associated with non-small-cell lung carcinoma (NSCLC) using whole-exome sequencing. (PubMed, Cancer Biomark)
    Our bioinformatics analysis identified KCNJ18, GPRIN2, TEKT4, HRNR, FOLR3, ESSRA, CTBP2, MPRIP, TBP, and FBXO6 may contribute to progression in NSCLC and could be used as new biomarkers for the treatment. The mechanism by which GPRIN2, KCNJ12, and TEKT4 contribute to tumorigenesis is unclear, but our results suggest they may play an important role in NSCLC and it is worth investigating in future.
    Journal
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    CTBP2 (C-Terminal Binding Protein 2) • MPRIP (Myosin Phosphatase Rho Interacting Protein) • KCNJ12 (Potassium Inwardly Rectifying Channel Subfamily J Member 12) • TEKT4 (Tektin 4) • GPRIN2 (G Protein Regulated Inducer Of Neurite Outgrowth 2) • HRNR (Hornerin)