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DRUG:

gp96-Ig vaccine

i
Other names: short gp96 vaccine, Ad100-gp96Ig-HLA A1, gp96 Ig-secreting allogeneic tumor cell-vaccine, gp96, gp96-Ig vaccine, gp96IG and HLA A1 transfected NSCLC cell line, AD100-A1-gp96Ig vaccine
Associations
Company:
Sylvester Comprehensive Cancer Center
Drug class:
Immunostimulant
Related drugs:
Associations
over3years
[VIRTUAL] TetTCRII-SeqHD: High-dimensional analysis of antigen-specific ex vivo CD4+ T cells (IMMUNOLOGY 2021)
We also found explicit differences in the phenotypes of antigen specific cells within the tumor and a paired healthy tissue sample. Conclusions In conclusion, we validate the use of a high-throughput technology for assessing the specificity, phenotype, TCR, and gene expression patterns in antigen-specific CD4+ T cells in peripheral blood and tumor infiltrating lymphocytes.
Preclinical
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CD8 (cluster of differentiation 8) • CD4 (CD4 Molecule)
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viagenpumatucel-L (HS-110) • gp96-Ig vaccine