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    GENE:

    GOSR2 (Golgi SNAP Receptor Complex Member 2)

    i
    Other names: GOSR2, Golgi SNAP Receptor Complex Member 2, GS27, Bos1, 27 KDa Golgi SNARE Protein, Membrin, EPM6, MYOS
    over2years
    Immunogenic landscape and risk score prediction based on unfolded protein response (UPR)-related molecular subtypes in hepatocellular carcinoma. (PubMed, Front Immunol)
    Moreover, ATF4 was upregulated, while GOSR2, PDIA6 and SRPRB were downregulated in sorafenib-treated HCC cells. The UPR-related prognostic signature containing four URGs exhibits high potential application value and performs well in the evaluation of effects of chemotherapy/immunotherapy and clinical prognosis.
    Journal • IO biomarker
    |
    ATF4 (Activating Transcription Factor 4) • GOSR2 (Golgi SNAP Receptor Complex Member 2) • PDIA6 (Protein Disulfide Isomerase Family A Member 6) • SRPRB (SRP Receptor Subunit Beta)
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    sorafenib