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    GENE:

    GNRH1 (Gonadotropin Releasing Hormone 1)

    i
    Other names: GNRH1, Gonadotropin Releasing Hormone 1, Progonadoliberin-1, Leuteinizing-Releasing Hormone, GNRH, LHRH, GRH, Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone, Prolactin Release-Inhibiting Factor, GnRH-Associated Peptide 1, Progonadoliberin I, Luliberin I, GNRH1, LNRH
    12ms
    Biological and therapeutic implications of sex hormone-related gene clustering in testicular cancer. (PubMed, Basic Clin Androl)
    Hormonal cluster #1 or #3 is an independent prognostic factor regarding poor progression-free survival. Hormonal cluster assignment also affects the predicted drug response with cluster-dependent susceptibility to specific novel therapeutic compounds.
    Journal
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    CYP17A1 (Cytochrome P450 Family 17 Subfamily A Member 1) • GNRH1 (Gonadotropin Releasing Hormone 1) • HSD17B2 (Hydroxysteroid 17-Beta Dehydrogenase 2) • PRL (Prolactin) • SRD5A1 (Steroid 5 Alpha-Reductase 1) • STAR (Steroidogenic Acute Regulatory Protein)
    almost2years
    Genome-wide analysis of two different regions of brain reveals the molecular changes of fertility related genes in rln3a-/- mutants in male Nile tilapia (Oreochromis niloticus). (PubMed, Gen Comp Endocrinol)
    In summary, the mutation of rln3a in male tilapia resulted in notable changes in circadian rhythm and disease-linked signaling pathways in the Di* and Hyp. These changes might account for the fertility defects observed in rln3a-/- male mutants in tilapia.
    Journal
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    ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator Like) • GNRH1 (Gonadotropin Releasing Hormone 1) • PER3 (Period Circadian Regulator 3)
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    GNRH1 expression