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    GENE:

    GMFG (Glia Maturation Factor Gamma)

    i
    Other names: GMFG, Glia Maturation Factor Gamma, GMF-GAMMA, GMF-Gamma
    Associations

    News

    Trials
    over1year
    Integrated Gene Expression Data-Driven Identification of Molecular Signatures, Prognostic Biomarkers, and Drug Targets for Glioblastoma. (PubMed, Biomed Res Int)
    Moreover, the identification of candidate compounds with potential interactions with GMFG offers exciting possibilities for targeted therapy development. However, further laboratory experiments are required to validate the role of GMFG in GBM pathogenesis and to assess the efficacy of potential therapeutic agents targeting this molecule.
    Journal
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    GMFG (Glia Maturation Factor Gamma)
    almost2years
    Identification of GMFG as a novel biomarker in IgA nephropathy based on comprehensive bioinformatics analysis. (PubMed, Heliyon)
    In addition, GMFG has a close relationship with the prognosis of malignancies and a range of immune cells. Our study suggests that GMFG could serve as a promising novel biomarker and potential therapeutic target for both IgAN and certain types of tumors.
    Journal
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    GMFG (Glia Maturation Factor Gamma)
    over2years
    High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer. (PubMed, Genes (Basel))
    In vitro, GMFG siRNA inhibited cell migration and invasion through the EMT pathway. The above data indicate that high expression of GMFG in TNBC is related to malignancy and that GMFG could be a biomarker for the detection of TNBC metastasis.
    Clinical data • Journal
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    GMFG (Glia Maturation Factor Gamma)
    almost3years
    Upregulation of lncRNA LANCL1-AS1 inhibits the progression of non-small-cell lung cancer via the miR-3680-3p/GMFG axis. (PubMed, Open Med (Wars))
    GMFG knockdown reversed LANCL1-AS1 overexpression-mediated inhibitory impact on NSCLC malignant behaviors. Collectively, LANCL1-AS1 upregulation inhibits the progression of NSCLC by modulating the miR-3680-3p/GMFG axis.
    Journal
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    GMFG (Glia Maturation Factor Gamma)