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    GENE:

    GK (Glycerol Kinase)

    i
    Other names: GK, Glycerol Kinase, GK1, GKD, ATP:Glycerol 3-Phosphotransferase, Glycerokinase
    3ms
    A long non-coding RNA SCAMP1 induces pancreatic ductal adenocarcinoma progression through miR-106a-5p/AGK signaling. (PubMed, Clin Exp Med)
    Knockdown of SCAMP1 expression reduced tumor cell growth, invasion, epithelial‑mesenchymal transition (EMT), and improved sensitivity to 5-fluorouracil (5-FU) in vitro and inhibited tumor cell xenograft growth in nude mice...The data from the current study demonstrated an oncogenic SCAMP1 activity in PDAC. Further study will investigate SCAMP1 as a tumor biomarker and novel target in control of PDAC clinically.
    Journal
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    AGK (Acylglycerol Kinase) • GK (Glycerol Kinase) • MIR106A (MicroRNA 106a)
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    5-fluorouracil