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BIOMARKER:

GHR-ALK fusion

i
Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor , GHR, Growth Hormone Receptor 2, GHBP, Growth Hormone Binding Protein, Somatotropin Receptor, GH Receptor, Truncated Growth Hormone Receptor, Mutant Growth Hormone Receptor, Serum Binding Protein, GHIP
Entrez ID:
3years
A novel GHR-ALK fusion gene in a patient with metastatic lung adenocarcinoma and its response to crizotinib: a case report. (PubMed, J Int Med Res)
She succumbed to her disease 11 months after the initial diagnosis. Our work provides evidence supporting the use of crizotinib in patients with metastatic LUAD harboring GHR-ALK.
Clinical • Journal
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ALK (Anaplastic lymphoma kinase) • EML4 (EMAP Like 4)
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ALK positive • ALK rearrangement • ALK fusion • GHR-ALK fusion
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Xalkori (crizotinib)