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    BIOMARKER:

    GHR-ALK fusion

    i
    Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor , GHR, Growth Hormone Receptor 2, GHBP, Growth Hormone Binding Protein, Somatotropin Receptor, GH Receptor, Truncated Growth Hormone Receptor, Mutant Growth Hormone Receptor, Serum Binding Protein, GHIP
    Entrez ID:
    238; 2690
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    over2years
    A novel GHR-ALK fusion gene in a patient with metastatic lung adenocarcinoma and its response to crizotinib: a case report. (PubMed, J Int Med Res)
    She succumbed to her disease 11 months after the initial diagnosis. Our work provides evidence supporting the use of crizotinib in patients with metastatic LUAD harboring GHR-ALK.
    Clinical • Journal
    |
    ALK (Anaplastic lymphoma kinase) • EML4 (EMAP Like 4)
    |
    ALK positive • ALK rearrangement • ALK fusion • GHR-ALK fusion
    |
    Xalkori (crizotinib)