^
    3d
    A Study to Investigate the Effect on Lung Function of BDA Formulated With a Next Generation Propellant Compared With an Approved Asthma Treatment (BDA With HFA Propellant) in Participants With Asthma (clinicaltrials.gov)
    P3, N=422, Active, not recruiting, AstraZeneca | Recruiting --> Active, not recruiting
    Enrollment closed
    3d
    Dex-Dex PNB: Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks (clinicaltrials.gov)
    P1/2, N=100, Active, not recruiting, University of Arizona | Trial completion date: Dec 2025 --> Dec 2026 | Trial primary completion date: Dec 2025 --> Dec 2026
    Trial completion date • Trial primary completion date
    |
    dexamethasone
    3d
    Palatal Wound Healing After Free Gingival Graft Surgery (clinicaltrials.gov)
    P=N/A, N=34, Recruiting, Kahramanmaras Sutcu Imam University
    New trial
    3d
    VENTURI (VENTilation Using Respiratory Imaging) (clinicaltrials.gov)
    P2, N=20, Not yet recruiting, University of Alabama at Birmingham | Initiation date: Dec 2025 --> Mar 2026
    Trial initiation date
    4d
    RETRIBUTE: Real-World Effectiveness of a Triple Combination BDP/FF/GB Extrafine in a Single Pressurised Metered Dose Inhaler in Brazilian COPD Patients (clinicaltrials.gov)
    P=N/A, N=396, Not yet recruiting, Chiesi Farmaceutica Ltda.
    New trial • Real-world evidence
    4d
    Anti-inflammatory activity and potential anti-inflammatory mechanisms of Artemisia scoparia essential oil. (PubMed, J Pharm Pharmacol)
    These findings suggest that ASEO has great potential as a natural anti-inflammatory agent, its key compositions and multiple anti-inflammatory mechanisms make it a promising candidate for further research and development for clinical applications.
    Journal
    |
    ER (Estrogen receptor) • TNFA (Tumor Necrosis Factor-Alpha) • EP300 (E1A binding protein p300) • PTGS2 (Prostaglandin-Endoperoxide Synthase 2) • PPARG (Peroxisome Proliferator Activated Receptor Gamma) • MPO (Myeloperoxidase) • PACERR (PTGS2 Antisense NFKB1 Complex-Mediated Expression Regulator RNA) • PPARA (Peroxisome Proliferator Activated Receptor Alpha)
    |
    dexamethasone
    4d
    VKH-OC: Oral Prednisolone Versus Posterior Sub-Tenon Triamcinolone for Acute Ocular VKH (clinicaltrials.gov)
    P=N/A, N=30, Completed, Benha University
    New trial
    |
    prednisolone
    4d
    Intra-sheath vs Extra-sheath Injection for De Quervain's Tenosynovitis (clinicaltrials.gov)
    P4, N=80, Recruiting, University of California, Davis | Trial primary completion date: Jun 2025 --> Jun 2026 | Trial completion date: Jun 2025 --> Jun 2026
    Trial completion date • Trial primary completion date
    |
    dexamethasone injection
    4d
    Fasudil improves neutrophilic asthma by influencing M1 macrophage polarization and the expression of the NF-κB/TLR-2/RPS3 pathway. (PubMed, Am J Transl Res)
    BALB/C mice were randomized into an NA group, a dexamethasone intervention group (DI, 1 mg/kg), and a Fasudil intervention group (FI, 40 mg/kg). Fasudil ameliorates NA via regulating M1 macrophage polarization, inhibiting the NF-κB/TLR-2/RPS3 pathway, and reducing pro-inflammatory cytokines, with S100A8/A9 and CXCL2 as potential biomarkers. These findings support Fasudil as a promising NA therapy, warranting further clinical translational research.
    Journal • IO biomarker
    |
    IL6 (Interleukin 6) • TNFA (Tumor Necrosis Factor-Alpha) • S100A8 (S100 Calcium Binding Protein A8) • S100A9 (S100 Calcium Binding Protein A9) • MMP9 (Matrix metallopeptidase 9) • IL1B (Interleukin 1, beta) • TLR2 (Toll Like Receptor 2)
    |
    dexamethasone
    4d
    Concomitant plasma cell myeloma and chronic myelomonocytic leukemia in elderly: diagnostic complexity, therapeutic challenges - case report and literature review. (PubMed, Ann Med Surg (Lond))
    She underwent leukapheresis, hydroxyurea for cytoreduction, and bortezomib-dexamethasone for myeloma. In elderly patients with cytopenias and monocytosis, thorough diagnostic workup is crucial. This case emphasizes the need for personalized therapy in complex hematologic overlap syndromes.
    Journal
    |
    NRAS (Neuroblastoma RAS viral oncogene homolog) • TET2 (Tet Methylcytosine Dioxygenase 2) • SDC1 (Syndecan 1)
    |
    NRAS mutation • TET2 mutation
    |
    bortezomib • dexamethasone • hydroxyurea
    5d
    Study on the Safety and Efficacy of Intratympanic Injection of Small Extracellular Vesicles Derived From Mesenchymal Stem Cells in Severe and Profound Sudden Sensorineural Hearing Loss (clinicaltrials.gov)
    P1/2, N=18, Not yet recruiting, The Affiliated Hospital of Qingdao University
    New P1/2 trial
    |
    dexamethasone injection
    5d
    Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre (clinicaltrials.gov)
    P=N/A, N=60, Recruiting, University of Nove de Julho | Not yet recruiting --> Recruiting | Trial completion date: Jul 2030 --> Nov 2030 | Initiation date: Oct 2025 --> Jan 2026
    Enrollment open • Trial completion date • Trial initiation date