^
2d
OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps (clinicaltrials.gov)
P3, N=72, Active, not recruiting, Optinose US Inc. | Recruiting --> Active, not recruiting | Trial completion date: Mar 2026 --> Jun 2026
Enrollment closed • Trial completion date
3d
Throat pack: Soaked Pharyngeal Packing Agents in Septoplasty (clinicaltrials.gov)
P3, N=65, Completed, Assiut University | Recruiting --> Completed
Trial completion
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dexamethasone
3d
Enrollment open
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prednisone • methylprednisolone sodium succinate
3d
New trial
3d
New trial
4d
Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs? (clinicaltrials.gov)
P1, N=84, Recruiting, Texas Tech University Health Sciences Center, El Paso | Trial completion date: Jan 2026 --> Jan 2028 | Trial primary completion date: Dec 2025 --> Dec 2027
Trial completion date • Trial primary completion date
5d
Trial completion
5d
Ventilation and Perfusion in Asthmatics (clinicaltrials.gov)
P4, N=40, Recruiting, University of Miami | Not yet recruiting --> Recruiting
Enrollment open
5d
Chrysophanol ameliorates ferroptosis in acute kidney injury by promoting SIRT3-mediated NRF2 deacetylation. (PubMed, Naunyn Schmiedebergs Arch Pharmacol)
To evaluate its prophylactic potential, WT mice were pretreated with CHR (20 and 40 mg/kg, i.g.) for three consecutive days prior to a single LPS injection (15 mg/kg, i.p.), while dexamethasone (2.5 mg/kg, i.p.) served as a positive control...CHR protects against LPS-induced AKI by inhibiting ferroptosis. This prophylactic process is linked to SIRT3-mediated deacetylation of NRF2, highlighting the potential of CHR as a preventive strategy for sepsis-induced renal injury.
Journal
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IL6 (Interleukin 6) • TNFA (Tumor Necrosis Factor-Alpha) • GPX4 (Glutathione Peroxidase 4) • SIRT3 (Sirtuin 3) • IL1B (Interleukin 1, beta)
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dexamethasone