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    BIOMARKER:

    FGF1 expression

    i
    Other names: FGF1, Fibroblast Growth Factor 1, AFGF, ECGF, Heparin-Binding Growth Factor 1, GLIO703, ECGFA, ECGFB, HBGF1, FGFA, Endothelial Cell Growth Factor, Alpha, Endothelial Cell Growth Factor, Beta, Fibroblast Growth Factor 1 (Acidic), ECGF-Beta, FGF-Alpha, HBGF-1, FGF-1, Beta-Endothelial Cell Growth Factor, Acidic Fibroblast Growth Factor, Endothelial Cell Growth Factor, ECGF-BETA, FGF-ALPHA
    Entrez ID:
    2246
    over1year
    Comprehensive in silico analysis of prognostic and immune infiltrates for FGFs in human ovarian cancer. (PubMed, J Ovarian Res)
    This study clarifies the relationship between FGFs and OC, which might provide new insights into the choice of prognostic biomarkers of OC patients.
    Journal
    |
    FGF2 (Fibroblast Growth Factor 2) • FGF18 (Fibroblast Growth Factor 18)
    |
    FGF1 expression
    over1year
    Exploring angiogenic pathways in breast cancer: Clinicopathologic correlations and prognostic implications based on gene expression profiles from a large-scale genomic dataset. (PubMed, PLoS One)
    In this dataset of patients with breast cancer, the expression levels of 8 different pro-angiogenic genes revealed remarkable differences in terms of their association with clinicopathologic tumor characteristics and prognosis. The expression of ANGPTs and PDGFs was associated with adverse tumor features, worse prognosis, and reduced survival in patients. Targeting ANGPTs and PDGF pathways could provide new insights for effective anti-angiogenic drugs in breast cancer.
    Journal • Gene Expression Profile
    |
    HER-2 (Human epidermal growth factor receptor 2) • HGF (Hepatocyte growth factor) • ANGPT2 (Angiopoietin 2) • FGF2 (Fibroblast Growth Factor 2) • PDGFA (Platelet Derived Growth Factor Subunit A) • PDGFB (Platelet Derived Growth Factor Subunit B)
    |
    HER-2 positive • HR negative • VEGFA expression • FGF1 expression • HER-2 positive + HR negative
    almost2years
    Fibroblast growth factor pathway promotes glycolysis by activating LDHA and suppressing LDHB in a STAT1-dependent manner in prostate cancer. (PubMed, J Transl Med)
    The FGF pathway facilitates glycolysis by activating LDHA and suppressing LDHB in a STAT1-dependent manner in PCa.
    Journal
    |
    LDHA (Lactate dehydrogenase A) • LDHB (L-lactate dehydrogenase B chain) • FGF2 (Fibroblast Growth Factor 2) • STAT1 (Signal Transducer And Activator Of Transcription 1)
    |
    FGF1 expression • LDHB overexpression