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    GENE:

    FAM43A (Family With Sequence Similarity 43 Member A)

    i
    Other names: FAM43A, Family With Sequence Similarity 43 Member A, Protein FAM43A, FLJ90022, Family With Sequence Similarity 43, Member A
    Associations

    News

    Trials
    3ms
    Using single-cell and transcriptome data to identify prognostic genes associated with SUMO-ylation and their molecular regulatory mechanisms in breast cancer. (PubMed, BMC Cancer)
    In this study, 8 SUMO-ylation related prognostic genes were identified in BRCA, namely GPC1, CAPZA1, NUDCD1, MTDH, COX7A1, PLK3, FAM43A and CEBPD, offering fresh perspectives on the prognosis of BRCA.
    Journal • BRCA Biomarker
    |
    CD8 (cluster of differentiation 8) • BRCA (Breast cancer early onset) • GPC1 (Glypican 1) • FAM43A (Family With Sequence Similarity 43 Member A) • MTDH (Metadherin)
    |
    sorafenib • Zarnestra (tipifarnib)
    3ms
    LDLRAD4 is a potential diagnostic and prognostic biomarker correlated with immune infiltration in myelodysplastic syndromes. (PubMed, Front Genet)
    These findings collectively identify LDLRAD4 as a promising therapeutic target for MDS. However, its clinical applicability warrants further investigation to validate its potential.
    Journal • IO biomarker
    |
    TGFB1 (Transforming Growth Factor Beta 1) • LDLR (Low Density Lipoprotein Receptor) • LDLRAD4 (Low Density Lipoprotein Receptor Class A Domain Containing 4) • FAM43A (Family With Sequence Similarity 43 Member A)
    almost2years
    An endothelial-related prognostic index for bladder cancer patients. (PubMed, Discov Oncol)
    We have effectively discerned pivotal genes from the endothelial cell perspective and constructed an EPI for BC patients, thereby offering promising prospects for precision medicine.
    Journal • Tumor mutational burden • IO biomarker
    |
    TMB (Tumor Mutational Burden) • CYTL1 (Cytokine Like 1) • FAM43A (Family With Sequence Similarity 43 Member A) • RBP7 (Retinol Binding Protein 7)
    |
    cisplatin • gemcitabine • docetaxel
    over2years
    Identification of novel stemness-based subtypes and construction of a prognostic risk model for patients with lung squamous cell carcinoma. (PubMed, Curr Stem Cell Res Ther)
    The stemness-based subtypes shed novel insights into the potential roles of LUSC-stemness in tumor heterogeneity, and our prognostic signatures offer a promising tool for prognosis prediction and guide therapeutic decisions in LUSC.
    Journal • IO biomarker
    |
    TP53 (Tumor protein P53) • TTN (Titin) • BMI1 (BMI1 proto-oncogene, polycomb ring finger) • EIF1AX (Eukaryotic Translation Initiation Factor 1A X-Linked) • FAM43A (Family With Sequence Similarity 43 Member A)
    |
    TP53 mutation • TTN mutation
    |
    dasatinib • paclitaxel • imatinib • sunitinib • saracatinib (AZD0530)