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    BIOMARKER:

    EZH2 rs201135441C>T

    i
    Other names: EZH2, ENX-1, EZH1, KMT6, KMT6A, Enhancer of zeste 2 polycomb repressive complex 2 subunit
    Entrez ID:
    2146
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    over2years
    Functional relationship of SNP (Ala490Thr) of an epigenetic gene EZH2 results in the progression and poor survival of ER+/tamoxifen treated breast cancer patients. (PubMed, J Genet)
    To the best of our knowledge, this is the first study on EZH2 polymorphism with breast cancer. In conclusion, these findings suggest that these variations in the EZH2 gene may have strong clinical significance as they can be targeted for prognosis, prevention and in drug development.
    Clinical • Journal
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    EZH2 (Enhancer of zeste 2 polycomb repressive complex 2 subunit)
    |
    EZH2 rs201135441C>T
    |
    tamoxifen