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DRUG:

ERG344

i
Other names: ERG344
Associations
Trials
Company:
Ergon Pharma
Drug class:
IRG1 inhibitor
Associations
Trials
almost5years
[VIRTUAL] ERG344: A novel IRG1 inhibitor for the treatment of colon cancer (AACR 2021)
Seven days after tumor inoculation, mice treated with ERG344 showed reduced tumor growth in the peritoneal cavity, which led to increased survival probability of the animals. The studies collectively suggest that IRG1 is a novel target for the treatment of primary and metastatic tumor growth in colorectal cancer and highlight the therapeutic potential of ERG344.
PD(L)-1 Biomarker • IO biomarker
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CD8 (cluster of differentiation 8) • PD-1 (Programmed cell death 1)
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CD8 expression
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ERG344