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    BIOMARKER:

    ERBB3 underexpression

    i
    Other names: ERBB3, HER3, LCCS2, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
    Entrez ID:
    2065
    Related biomarkers:
    Expression
    Mutation
    CNA
    Others
    over3years
    Down-Regulation of USP8 Suppresses HER-3 Positive Gastric Cancer Cells Proliferation. (PubMed, Onco Targets Ther)
    In vivo studies demonstrated that down-regulation of USP8 inhibited HER-3 positive tumors growth. Down-regulation of USP8 inhibits HER-3 positive GC cells proliferation in vivo and in vitro, which indicate that USP8 represents a feasible choice as a therapeutic target for HER-3 positive GC cells.
    Journal
    |
    ERBB3 (V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3)
    |
    ERBB3 expression • ERBB3 overexpression • ERBB3 underexpression