Almost 70-80% of BRCA2-mutated BC are estrogen receptor (ER)-positive, which is a particular type of ER-positive BC that differs from sporadic ER-positive BC. This article reviews the clinicopathological features, treatment, and prognosis of ER-positive and BRCA2-mutated BC to provide a reference for clinical decision-making.
11 months ago
Review • Journal • BRCA Biomarker
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ER (Estrogen receptor) • BRCA2 (Breast cancer 2, early onset)
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BRCA2 mutation • ER positive • BRCA2 positive • ER positive + BRCA2 mutation