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DRUG:

epratuzumab-thorium-227 (BAY1862864)

i
Other names: BAY1862864, targeted thorium conjugate, thorium-227 linked to epratuzumab using targeted thorium conjugates platform, epratuzumab Th-227, BAY 1862864, BAY-1862864
Associations
Company:
Bayer
Drug class:
Apoptosis stimulant, CD22 modulator
Associations
over3years
Thorium-227-Labeled Anti-CD22 Antibody (BAY 1862864) in Relapsed/Refractory CD22-Positive Non-Hodgkin Lymphoma: A First-in-Human, Phase I Study. (PubMed, Cancer Biother Radiopharm)
BAY 1862864 was safe and tolerated in patients with R/R-NHL. The Clinical Trial Registration numbers: NCT02581878 and EudraCT 2014-004140-36.
P1 data • Journal
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CD22 (CD22 Molecule)
|
CD22 positive
|
epratuzumab-thorium-227 (BAY1862864)
almost5years
Clinical • Trial completion
|
CD22 (CD22 Molecule)
|
CD22 positive
|
epratuzumab-thorium-227 (BAY1862864)
over5years
Safety and Tolerability of BAY1862864 Injection in Subjects With Relapsed or Refractory CD22-positive Non-Hodgkin's Lymphoma (clinicaltrials.gov)
P1; N=21; Active, not recruiting; Sponsor: Bayer; Recruiting --> Active, not recruiting; N=60 --> 21; Trial completion date: Oct 2020 --> Dec 2019; Trial primary completion date: Mar 2020 --> Apr 2019
Trial completion date • Trial primary completion date • Enrollment change • Enrollment closed • Clinical
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CD22 (CD22 Molecule)
|
CD22 positive
|
epratuzumab-thorium-227 (BAY1862864)
almost6years
Clinical • Trial completion date
|
CD22 (CD22 Molecule)
|
CD22 positive
|
epratuzumab-thorium-227 (BAY1862864)