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DRUG:

fosaprepitant

i
Other names: MK-0517, ONO-7847, L-785,298 , aprepitant prodrug
Associations
Trials
Company:
Generic mfg.
Drug class:
NK-1 antagonist
Associations
Trials
1m
QLM2010-301: To Evaluate the Efficacy and Safety of QLM2010 for Prevention of Chemotherapy-induced Nausea and Vomiting After Highly Emetogenic Chemotherapy. (clinicaltrials.gov)
P3, N=665, Completed, Qilu Pharmaceutical Co., Ltd. | Recruiting --> Completed | Trial completion date: Mar 2026 --> Oct 2025 | Trial primary completion date: Dec 2025 --> Aug 2025
Trial completion • Trial completion date • Trial primary completion date
|
dexamethasone injection • fosaprepitant
2ms
Prevention of Delayed CINV after Autologous Transplant: Olanzapine-Containing Regimen vs. Dexamethasone-Containing Regimen (ChiCTR2500110061)
P3, N=92, Not yet recruiting, The affiliated people's hospital of Ningbo University; The affiliated people's hospital of Ningbo University
New P3 trial
|
FTO (Alpha-Ketoglutarate-Dependent Dioxygenase FTO)
|
dexamethasone • fosaprepitant • olanzapine
3ms
BARF RCT: Broadening Antiemetics Research by Comparing the Effectiveness of Fosaprepitant and Metoclopramide (clinicaltrials.gov)
P4, N=212, Not yet recruiting, Montefiore Medical Center | Initiation date: Jun 2025 --> May 2026 | Trial primary completion date: Mar 2026 --> Feb 2027 | Phase classification: P2/3 --> P4 | Trial completion date: Mar 2026 --> Feb 2027
Phase classification • Trial completion date • Trial initiation date • Trial primary completion date
|
fosaprepitant
4ms
Antiemetic Fosaprepitant To Remedy Nausea and Vomiting (clinicaltrials.gov)
P2/3, N=250, Recruiting, Montefiore Medical Center | Trial completion date: May 2025 --> Jun 2026 | Trial primary completion date: May 2025 --> Jun 2026
Trial completion date • Trial primary completion date
|
fosaprepitant • ondansetron intravenous
4ms
Nanocrystalline Megestrol for Managing Chemotherapy-Induced Nausea and Vomiting (clinicaltrials.gov)
P3, N=126, Not yet recruiting, The First Affiliated Hospital of Xinxiang Medical College
New P3 trial
|
megestrol • medroxyprogesterone • fosaprepitant • ondansetron
5ms
Enrollment open
|
fosaprepitant • ondansetron intravenous
5ms
New P3 trial
|
dexamethasone injection • fosaprepitant
7ms
A prospective, single-arm clinical study of dolasetron mesylate injection in the prevention of nausea and vomiting caused by highly emetogenic chemotherapy (ChiCTR2500101930)
P4, N=233, Not yet recruiting, Shao Yi Fu Hospital Affiliated to Zhejiang University School of Medicine; Shao Yi Fu Hospital Affiliated to Zhejiang University School of Medicine
New P4 trial
|
anastrozole • dexamethasone • fosaprepitant
9ms
Triple Therapy of Dexamethasone, Palonosetron, and Fosaprepitant As PONV Prevention (clinicaltrials.gov)
P=N/A, N=144, Enrolling by invitation, Samsung Medical Center | Trial completion date: Mar 2024 --> Dec 2025 | Trial primary completion date: Mar 2024 --> Dec 2025
Trial completion date • Trial primary completion date
|
dexamethasone • fosaprepitant
1year
New P2/3 trial
|
fosaprepitant
1year
Enrollment open
|
dexamethasone • melphalan • fosaprepitant • olanzapine • ondansetron