In a phase I/II clinical trial, the safety, tolerability, and pharmacological effects of orally administered EDP1503 in combination with pembrolizumab are being evaluated in multiple tumor types: microsatellite stable (MSS) metastatic colorectal cancer, triple-negative breast cancer, and a basket of PD-1 relapsed solid tumors. Legal entity responsible for the study The authors. Funding Evelo Biosciences.
over 4 years ago
PD(L)-1 Biomarker • IO biomarker
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CD8 (cluster of differentiation 8) • IFNG (Interferon, gamma)