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    GENE:

    DUXAP10 (Double Homeobox A Pseudogene 10)

    i
    Other names: DUXAP10, Double Homeobox A Pseudogene 10, LNMAT1
    Associations

    News

    Trials
    2ms
    Long Non-Coding RNA DUXAP10 Promotes Tumorigenesis and Metastasis in Anaplastic Thyroid Cancer. (PubMed, Cancers (Basel))
    Our two DUXAP10-CRISPRi cell lines significantly reduced the rapid growth and metastatic behaviors characteristic of ATC, affecting proliferation, viability, clonogenicity, apoptosis, invasion, migration, tumorigenesis, and metastasis. Thus, DUXAP10 is a proposed prognostic marker and therapeutic target for ATC disease propagation and progression.
    Journal
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    DUXAP10 (Double Homeobox A Pseudogene 10)
    2years
    Development and validation of a novel stemness-related prognostic model for neuroblastoma using integrated machine learning and bioinformatics analyses. (PubMed, Transl Pediatr)
    Our findings confirm the influence of CSC features in NB prognosis. The newly developed NB stemness-related four-gene signature prognostic signature could facilitate the prognostic prediction, and the identified hub genes may serve as promising targets for individualized treatments.
    Journal • Machine learning
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    MYCN (MYCN Proto-Oncogene BHLH Transcription Factor) • DIRAS3 (DIRAS Family GTPase 3) • ERCC6 (Excision repair cross-complementation group 6) • DUXAP10 (Double Homeobox A Pseudogene 10)
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    MYCN amplification