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    GENE:

    DTX4 (Deltex E3 Ubiquitin Ligase 4)

    i
    Other names: DTX4, Deltex E3 Ubiquitin Ligase 4, RNF155, KIAA0937, RING-Type E3 Ubiquitin Transferase DTX4, E3 Ubiquitin-Protein Ligase DTX4, RING Finger Protein 155, Protein Deltex-4, Deltex4, Deltex Homolog 4 (Drosophila), Deltex 4, E3 Ubiquitin Ligase, Deltex 4 Homolog, Deltex Homolog 4
    Associations

    News

    Trials
    over1year
    Construction and validation of a ubiquitination-related prognostic risk score signature in breast cancer. (PubMed, Heliyon)
    This study established an risk score signature consisting of six ubiquitination genes, that can accurately forecast the outcome of patients with BC using multiple datasets. It can provide personalized and targeted assistance to provide the evaluation and therapy of individuals having BC.
    Journal
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    BIRC3 (Baculoviral IAP repeat containing 3) • ATG5 (Autophagy Related 5) • FBXL20 (F-Box And Leucine Rich Repeat Protein 20) • DTX4 (Deltex E3 Ubiquitin Ligase 4)
    2years
    The role of MAPK, notch and Wnt signaling pathways in papillary thyroid cancer: Evidence from a systematic review and meta-analyzing microarray datasets employing bioinformatics knowledge and literature. (PubMed, Biochem Biophys Rep)
    To further explain these findings, it was discovered that the mRNA expression levels of these seven genes and the remaining 12 genes were shown to be substantially linked with the results of the experimental literature investigations on the PTC. Our research found nineteen panels of genes that could be involved in the PTC progression and metastasis and the immune system infiltration of these cancers.
    Review • Journal
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    FGFR2 (Fibroblast growth factor receptor 2) • FGF7 (Fibroblast Growth Factor 7) • GADD45B (Growth Arrest And DNA Damage Inducible Beta) • DTX4 (Deltex E3 Ubiquitin Ligase 4)
    over2years
    Invasive Breast Cancer: miR-24-2 Targets Genes Associated with Survival and Sensitizes MDA-MB-231 Cells to Berberine. (PubMed, OMICS)
    In all, this study reports on the novel target genes of miR-24-2 in invasive breast cancer/TNBC, and that miR-24-2 sensitizes MDA-MB-231 cells to berberine. These data lend evidence for the translational potentials of miR-24-2 for invasive breast cancer diagnostic and therapeutic innovation.
    Journal • BRCA Biomarker
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    BRCA (Breast cancer early onset) • HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ Beta 1) • IL1R1 (Interleukin 1 receptor, type I) • L1CAM (L1 cell adhesion molecule) • MIR24-2 (MicroRNA 24-2) • RACGAP1 (Rac GTPase activating protein 1) • SOD2 (Superoxide Dismutase 2) • DTX4 (Deltex E3 Ubiquitin Ligase 4) • HLA-DQB2 (Major Histocompatibility Complex, Class II, DQ Beta 2) • LYRM7 (LYR Motif Containing 7) • SAP30L (SAP30 Like) • SLC1A3 (Solute Carrier Family 1 Member 3) • TIMM17A (Translocase Of Inner Mitochondrial Membrane 17A)