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    BIOMARKER:

    DPP3 overexpression

    i
    Other names: Dipeptidyl Peptidase 3, Dipeptidyl Aminopeptidase III, Dipeptidyl Arylamidase III, Dipeptidyl Peptidase III, Enkephalinase B, DPP III, Dipeptidylpeptidase III, Dipeptidyl-Peptidase 3, Dipeptidylpeptidase 3, DPPIII, DPP3
    Entrez ID:
    10072
    1m
    Dipeptidyl peptidase 3 (DPP3) inhibits immune escape of gastric cancer cells through down-regulation of major histocompatibility complex class I chain-related gene B (MICB) expression (PubMed, Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi)
    Knocking down MICB could reverse the phenotypic changes induced by high DPP3 expression. Conclusion DPP3 inhibits the immune escape of gastric cancer cells by downregulating MICB expression.
    Journal
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    NCAM1 (Neural cell adhesion molecule 1) • DPP3 (Dipeptidyl Peptidase 3) • MICB (MHC Class I Polypeptide-Related Sequence B)
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    DPP3 overexpression