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    DRUG:

    docetaxel-HPG (STK-01)

    i
    Other names: STK-01
    Associations

    News

    Trials
    Company:
    Sitka Biopharma
    Drug class:
    Tubulin polymerization promoter, Microtubule stabilizer
    Related drugs:
    Associations

    News

    Trials
    over3years
    [VIRTUAL] STK-012, an alpha/beta selective IL-2 mutein for the activation of the antigen-activated T cells in solid tumor (AACR 2021)
    STK-012 selectively induced memory T cell expansion, including CD28+ CD95+ CD8 T cells. In summary, STK-012 avoids IL-2 mediated toxicity and may enable the specific expansion of antigen activated memory T cells in cancer patients, leading to durable tumor response.
    PD(L)-1 Biomarker • IO biomarker
    |
    CD8 (cluster of differentiation 8) • CD22 (CD22 Molecule) • IL2 (Interleukin 2) • FAS (Fas cell surface death receptor) • FCGR2A (Fc fragment of IgG receptor IIa) • FCGR2B (Fc Fragment Of IgG Receptor IIb)
    |
    STK-012 • docetaxel-HPG (STK-01)