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DRUG:

docetaxel-HPG (STK-01)

i
Other names: STK-01
Associations
Trials
Company:
Sitka Biopharma
Drug class:
Tubulin polymerization promoter, Microtubule stabilizer
Associations
Trials
3years
[VIRTUAL] STK-012, an alpha/beta selective IL-2 mutein for the activation of the antigen-activated T cells in solid tumor (AACR 2021)
STK-012 selectively induced memory T cell expansion, including CD28+ CD95+ CD8 T cells. In summary, STK-012 avoids IL-2 mediated toxicity and may enable the specific expansion of antigen activated memory T cells in cancer patients, leading to durable tumor response.
PD(L)-1 Biomarker • IO biomarker
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CD8 (cluster of differentiation 8) • CD22 (CD22 Molecule) • IL2 (Interleukin 2) • FAS (Fas cell surface death receptor) • FCGR2A (Fc fragment of IgG receptor IIa) • FCGR2B (Fc Fragment Of IgG Receptor IIb)
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STK-012 • docetaxel-HPG (STK-01)