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    BIOMARKER:

    DIRAS3 overexpression

    i
    Other names: DIRAS3, DIRAS Family GTPase 3, Distinct Subgroup Of The Ras Family Member 3, Rho-Related GTP-Binding Protein RhoI, DIRAS Family, GTP-Binding RAS-Like 3, Ras Homolog Gene Family, Member I, GTP-Binding Protein Di-Ras3, NOEY2, ARHI, RHOI
    Entrez ID:
    9077
    Related biomarkers:
    Expression
    almost4years
    GTP-binding protein Di-RAS3 diminishes the migration and invasion of non-small cell lung cancer by inhibiting the RAS/extracellular-regulated kinase pathway. (PubMed, Bioengineered)
    Mechanistically, DIRAS3 may inhibit the migration and invasion of NSCLC cells by inhibiting the RAS/extracellular-regulated kinase (ERK) signaling pathway. Collectively, our findings indicate that DIRAS3 could serve as a potential therapeutic target biomarker for NSCLC.
    Journal
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    DIRAS3 (DIRAS Family GTPase 3)
    |
    DIRAS3 expression • DIRAS3 overexpression