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    GENE:

    DFNB31 (Deafness, Autosomal Recessive 31)

    i
    Other names: DFNB31, Whirlin, Autosomal Recessive Deafness Type 31 Protein, Deafness, Autosomal Recessive 31, CASK-Interacting Protein CIP98, KIAA1526, PDZD7B, CIP98, USH2D
    3ms
    Molecular biomarkers of sintilimab plus lenvatinib in hepatitis-B-virus-associated hepatocellular carcinoma. (PubMed, World J Hepatol)
    Sintilimab plus lenvatinib showed heterogeneous efficacy in HCC. High LINC01554 expression, elevated CD4+ Tcm cells, and solitary tumors may serve as predictive biomarkers for prolonged disease control.
    Journal • IO biomarker
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    CD4 (CD4 Molecule) • CUX1 (cut like homeobox 1) • DFNB31 (Deafness, Autosomal Recessive 31) • FANCD2 (FA Complementation Group D2)
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    Tyvyt (sintilimab) • Lenvima (lenvatinib)
    10ms
    OTX2 expression contributes progression of gastric cancer in young adults. (PubMed, Sci Rep)
    Therefore, OTX2 plays important roles in restraining the differentiation and promoting progression of gastric cancer cells in young adults. Moreover, OTX2/CEBPB signal axis is likely to be a key molecular event in regulating the differentiation of gastric cancer cells in young adults.
    Journal
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    CD73 (5'-Nucleotidase Ecto) • NT5E (5'-Nucleotidase Ecto) • MLLT3 (MLLT3 Super Elongation Complex Subunit) • DFNB31 (Deafness, Autosomal Recessive 31) • TBX1 (T-Box Transcription Factor 1) • ACAN (Aggrecan) • DUSP5 (Dual Specificity Phosphatase 5) • BMP4 (Bone Morphogenetic Protein 4)