^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    DRUG:

    dexamethasone injection

    Associations

    News

    Trials
    Company:
    Generic mfg.
    Drug class:
    GCR agonist, Steroid receptor agonist
    Related drugs:
    Associations

    News

    Trials
    3d
    STAR: Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS (clinicaltrials.gov)
    P=N/A, N=300, Recruiting, Peking Union Medical College Hospital | Not yet recruiting --> Recruiting
    Enrollment open
    |
    dexamethasone injection
    7d
    Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia (clinicaltrials.gov)
    P4, N=90, Not yet recruiting, Assiut University
    New P4 trial
    |
    dexamethasone injection
    8d
    Dexamethasone vs Ondansetron After Cesarean Delivery (clinicaltrials.gov)
    P4, N=100, Completed, Beth Israel Deaconess Medical Center | Not yet recruiting --> Completed | Trial completion date: Mar 2026 --> Apr 2024 | Trial primary completion date: Mar 2026 --> Apr 2024
    Trial completion • Trial completion date • Trial primary completion date
    |
    dexamethasone injection • ondansetron intravenous
    8d
    Real MM: STUDY COMPARING TWO STANDARD TREATMENTS IN AUTOLOGOUS STEM CELL TRANSPLANTATION INELIGIBLE POPULATION AFFECTED BY MULTIPLE MYELOMA (clinicaltrials.gov)
    P4, N=450, Recruiting, University of Turin, Italy | Trial primary completion date: Jan 2024 --> Jan 2025
    Trial primary completion date
    |
    lenalidomide • bortezomib • melphalan • Darzalex Faspro (daratumumab/hyaluronidase) • dexamethasone injection
    9d
    Randomized Phase II Study of ADT + Abiraterone vs ADT + Docetaxel + Abiraterone (clinicaltrials.gov)
    P2, N=150, Active, not recruiting, Northwestern University | Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2028 --> May 2024
    Enrollment closed • Trial primary completion date • Metastases
    |
    docetaxel • abiraterone acetate • dexamethasone injection
    10d
    Enhanced Recovery After Surgery (ERAS) Pathway for Primary Hip and Knee Arthroplasty (clinicaltrials.gov)
    P=N/A, N=640, Completed, West China Hospital | Recruiting --> Completed
    Trial completion • Surgery
    |
    dexamethasone injection
    18d
    Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery (clinicaltrials.gov)
    P4, N=90, Recruiting, Poznan University of Medical Sciences | Not yet recruiting --> Recruiting
    Enrollment open • Surgery
    |
    dexamethasone injection
    18d
    STAR: Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS (clinicaltrials.gov)
    P=N/A, N=300, Not yet recruiting, Peking Union Medical College Hospital
    New trial
    |
    dexamethasone injection
    18d
    ALCYONE: A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma (clinicaltrials.gov)
    P3, N=706, Active, not recruiting, Janssen Research & Development, LLC | Trial completion date: Feb 2024 --> Jun 2024
    Trial completion date • Combination therapy
    |
    bortezomib • Darzalex (daratumumab) • melphalan • Darzalex Faspro (daratumumab/hyaluronidase) • dexamethasone injection
    18d
    Testing the Combination of Inotuzumab Ozogamicin and Lower Dose Chemotherapy Compared to Usual Chemotherapy for Adults With B-Cell Acute Lymphoblastic Leukemia or B-Cell Lymphoblastic Lymphoma (clinicaltrials.gov)
    P2, N=66, Recruiting, Alliance for Clinical Trials in Oncology | Trial primary completion date: May 2028 --> May 2025
    Trial primary completion date
    |
    CD20 (Membrane Spanning 4-Domains A1) • CD22 (CD22 Molecule)
    |
    CD20 expression • CD22 positive
    |
    clonoSEQ
    |
    Rituxan (rituximab) • cytarabine • doxorubicin hydrochloride • cyclophosphamide • methotrexate • Besponsa (inotuzumab ozogamicin) • vincristine • mercaptopurine • dexamethasone injection
    21d
    Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients (clinicaltrials.gov)
    P2/3, N=410, Recruiting, Acacia Pharma Ltd | Not yet recruiting --> Recruiting | Trial completion date: Dec 2024 --> Dec 2025 | Trial primary completion date: Jun 2024 --> Jun 2025
    Enrollment open • Trial completion date • Trial primary completion date
    |
    dexamethasone injection
    21d
    MonumenTAL-6: A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide (clinicaltrials.gov)
    P3, N=795, Recruiting, Janssen Research & Development, LLC | Trial primary completion date: Jun 2027 --> Apr 2026
    Trial primary completion date • Combination therapy
    |
    lenalidomide • bortezomib • pomalidomide • Empliciti (elotuzumab) • Talvey (talquetamab-tgvs) • Tecvayli (teclistamab-cqyv) • dexamethasone injection
    22d
    12-C-0107: Carfilzomib, Lenalidomide, and Dexamethasone for Smoldering Multiple Myeloma (clinicaltrials.gov)
    P2, N=55, Active, not recruiting, National Cancer Institute (NCI) | Trial completion date: Jun 2025 --> Jun 2028
    Trial completion date
    |
    Chr t(4;14)
    |
    lenalidomide • carfilzomib • dexamethasone injection
    23d
    KETOPAIN: Non-steroidal Anti-inflammatory in Cardiac Surgery (clinicaltrials.gov)
    P=N/A, N=238, Recruiting, Centre Hospitalier Universitaire, Amiens
    New trial • Surgery
    |
    dexamethasone injection
    23d
    Hormonal Mechanisms of Sleep Restriction - Axis Study (clinicaltrials.gov)
    P1, N=80, Active, not recruiting, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Trial completion date: Dec 2024 --> Mar 2025
    Trial completion date
    |
    dexamethasone injection
    27d
    Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial (clinicaltrials.gov)
    P2, N=200, Not yet recruiting, Emory University | Initiation date: Mar 2024 --> Jul 2024
    Trial initiation date
    |
    Hemady (dexamethasone tablets) • dexamethasone injection
    27d
    Linperlisib Combined With Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-cell Lymphoma (clinicaltrials.gov)
    P1/2, N=43, Recruiting, Beijing Tongren Hospital
    New P1/2 trial • Metastases
    |
    AiRuiKa (camrelizumab) • Oncaspar liquid (pegaspargase) • Itari (linperlisib) • dexamethasone injection
    29d
    Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia (clinicaltrials.gov)
    P1, N=130, Active, not recruiting, Amgen | Recruiting --> Active, not recruiting | Phase classification: P1b/2 --> P1
    Enrollment closed • Phase classification • Combination therapy
    |
    cytarabine • cyclophosphamide • vincristine • daunorubicin • carfilzomib • mitoxantrone • Oncaspar liquid (pegaspargase) • mercaptopurine • dexamethasone injection
    1m
    Effectiveness of Cervical Transforaminal Epidural Steroid Injection (clinicaltrials.gov)
    P4, N=33, Completed, University of Utah | Active, not recruiting --> Completed
    Trial completion
    |
    dexamethasone injection
    1m
    Ocarina II: A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (clinicaltrials.gov)
    P3, N=236, Active, not recruiting, Hoffmann-La Roche | Trial primary completion date: Mar 2023 --> Apr 2025
    Trial primary completion date • Head-to-Head
    |
    Ocrevus (ocrelizumab) • dexamethasone injection • methylprednisolone sodium succinate
    1m
    Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL (clinicaltrials.gov)
    P1, N=17, Completed, Amgen | Phase classification: P1b --> P1
    Phase classification • Combination therapy
    |
    Blincyto (blinatumomab) • dexamethasone injection • zeluvalimab (AMG 404)
    1m
    AALL0434: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma (clinicaltrials.gov)
    P3, N=1895, Active, not recruiting, National Cancer Institute (NCI)
    Trial completion date
    |
    CD20 (Membrane Spanning 4-Domains A1) • CD8 (cluster of differentiation 8) • CD22 (CD22 Molecule) • CD34 (CD34 molecule) • CD5 (CD5 Molecule) • CD7 (CD7 Molecule) • CD2 (CD2 Molecule) • MPO (Myeloperoxidase)
    |
    CD22 expression
    |
    cytarabine • doxorubicin hydrochloride • cyclophosphamide • methotrexate • vincristine • daunorubicin • leucovorin calcium • Oncaspar liquid (pegaspargase) • nelarabine • mercaptopurine • thioguanine • Hemady (dexamethasone tablets) • Kidrolase (L-asparaginase) • Leunase (L-asparaginase) • Spectrila (asparaginase Escherichia coli) • Starasid (cytarabine ocfosfate) • dexamethasone injection
    1m
    Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis (clinicaltrials.gov)
    P3, N=338, Not yet recruiting, SWOG Cancer Research Network | Initiation date: Oct 2023 --> May 2024
    Trial initiation date
    |
    CD34 (CD34 molecule)
    |
    bortezomib • cyclophosphamide • melphalan • Darzalex Faspro (daratumumab/hyaluronidase) • Hemady (dexamethasone tablets) • dexamethasone injection
    1m
    Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia (clinicaltrials.gov)
    P2, N=80, Recruiting, Mayo Clinic | N=55 --> 80
    Enrollment change
    |
    IDH1 (Isocitrate dehydrogenase (NADP(+)) 1) • BCL2 (B-cell CLL/lymphoma 2) • IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2) • DNMT3A (DNA methyltransferase 1) • SF3B1 (Splicing Factor 3b Subunit 1) • TET2 (Tet Methylcytosine Dioxygenase 2) • SRSF2 (Serine and arginine rich splicing factor 2) • U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1) • CD4 (CD4 Molecule) • ZRSR2 (Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 2)
    |
    IDH2 mutation • DNMT3A mutation • TET2 mutation • SF3B1 mutation • EZH2 mutation • SRSF2 mutation • U2AF1 mutation
    |
    cisplatin • carboplatin • gemcitabine • Rituxan (rituximab) • cytarabine • cyclophosphamide • ifosfamide • oxaliplatin • etoposide IV • decitabine • Hemady (dexamethasone tablets) • Mabtas (rituximab biosimilar) • Starasid (cytarabine ocfosfate) • dexamethasone injection
    2ms
    Phase Ib Study of SAR650984 in Combination With Carfilzomib for Treatment of Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov)
    P1, N=83, Active, not recruiting, Thomas Martin, MD | Recruiting --> Active, not recruiting
    Enrollment closed • Combination therapy
    |
    carfilzomib • Sarclisa (isatuximab-irfc) • dexamethasone injection
    2ms
    NCI-2018-02830: Daratumumab, Bortezomib, and Dexamethasone Followed by Daratumumab, Ixazomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov)
    P2, N=40, Active, not recruiting, M.D. Anderson Cancer Center | Recruiting --> Active, not recruiting | N=60 --> 40
    Enrollment closed • Enrollment change
    |
    bortezomib • Ninlaro (ixazomib) • Darzalex (daratumumab) • dexamethasone injection
    2ms
    Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial) (clinicaltrials.gov)
    P3, N=520, Completed, Oxford University Clinical Research Unit, Vietnam | Active, not recruiting --> Completed | Trial completion date: Jun 2024 --> Apr 2023
    Trial completion • Trial completion date
    |
    dexamethasone injection
    2ms
    Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis (clinicaltrials.gov)
    P3, N=720, Active, not recruiting, Oxford University Clinical Research Unit, Vietnam | Recruiting --> Active, not recruiting
    Enrollment closed • Head-to-Head
    |
    dexamethasone injection
    2ms
    Effect of Ketorolac on Post Adenotonsillectomy Pain (clinicaltrials.gov)
    P4, N=63, Completed, Emory University | Recruiting --> Completed | N=120 --> 63 | Trial completion date: Sep 2024 --> Aug 2023 | Trial primary completion date: Sep 2024 --> Aug 2023
    Trial completion • Enrollment change • Trial completion date • Trial primary completion date
    |
    dexamethasone injection • ondansetron
    2ms
    Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or CCUS (clinicaltrials.gov)
    P2, N=55, Recruiting, Mayo Clinic | Trial completion date: Mar 2024 --> Mar 2026 | Trial primary completion date: Mar 2024 --> Dec 2025
    Trial completion date • Trial primary completion date
    |
    IDH1 (Isocitrate dehydrogenase (NADP(+)) 1) • BCL2 (B-cell CLL/lymphoma 2) • IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2) • DNMT3A (DNA methyltransferase 1) • SF3B1 (Splicing Factor 3b Subunit 1) • TET2 (Tet Methylcytosine Dioxygenase 2) • SRSF2 (Serine and arginine rich splicing factor 2) • U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1) • CD4 (CD4 Molecule) • ZRSR2 (Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 2)
    |
    IDH2 mutation • DNMT3A mutation • TET2 mutation • SF3B1 mutation • EZH2 mutation • SRSF2 mutation • U2AF1 mutation
    |
    cisplatin • carboplatin • gemcitabine • Rituxan (rituximab) • cytarabine • cyclophosphamide • ifosfamide • oxaliplatin • etoposide IV • Hemady (dexamethasone tablets) • Starasid (cytarabine ocfosfate) • dexamethasone injection
    2ms
    I-SPY_COVID: I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients (clinicaltrials.gov)
    P2, N=1500, Recruiting, QuantumLeap Healthcare Collaborative | Trial completion date: Nov 2024 --> Jul 2030 | Trial primary completion date: Jul 2023 --> Jul 2028
    Trial completion date • Trial primary completion date
    |
    imatinib • dexamethasone injection
    2ms
    Dexamethasone in Total Knee Arthroplasty (clinicaltrials.gov)
    P4, N=429, Recruiting, Rush University Medical Center | Trial primary completion date: Feb 2024 --> May 2024
    Trial primary completion date
    |
    dexamethasone injection
    2ms
    Erector Spinae Plane Block Versus Intercostal for VATS (clinicaltrials.gov)
    P=N/A, N=100, Completed, McGill University Health Centre/Research Institute of the McGill University Health Centre | Unknown status --> Completed
    Trial completion • Surgery
    |
    dexamethasone injection
    2ms
    ITHACA: A Phase 3 Randomized, Open-label, Multicenter Study of Isatuximab (SAR650984) in Combination With Lenalidomide and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With High-risk Smoldering Multiple Myeloma (clinicaltrials.gov)
    P3, N=337, Active, not recruiting, Sanofi | Trial primary completion date: Jun 2028 --> Nov 2030
    Trial primary completion date • Combination therapy
    |
    lenalidomide • Sarclisa (isatuximab-irfc) • dexamethasone injection
    2ms
    Effect of Intravenous Dexmedetomidine Versus Dexamethasone for Management of Repound Pain After Supraclavicular Brachial Plexus Block (clinicaltrials.gov)
    P1, N=111, Not yet recruiting, Assiut University
    New P1 trial
    |
    dexamethasone injection
    2ms
    HLH Syndrome in a Community Hospital: The Challenge of an Early Diagnosis. (PubMed, Pediatric Health Med Ther)
    Infection was identified in 8 of 9 patients: adenovirus, HHV6, EBV, and Streptococcus Group A. Only 2 patients received HLH-2004 therapy (dexamethasone, etoposide, cyclosporin-A) and the others received dexamethasone and/or intravenous gamma globulins (IVIG), with rapid resolution of fever (median 2 days). Early intervention with corticosteroids and/or IVIG may prevent deterioration, spare them from chemotherapy and provide time for more elaborate testing to identify true HLH. Unfortunately, mortality remains a significant risk for these children.
    Journal
    |
    IL2 (Interleukin 2) • UNC13D (Unc-13 Homolog D) • STXBP2 (Syntaxin Binding Protein 2)
    |
    IL2 elevation
    |
    etoposide IV • dexamethasone injection
    2ms
    Oral Dexamethasone for Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy (clinicaltrials.gov)
    P3, N=814, Recruiting, Mansoura University | Not yet recruiting --> Recruiting
    Enrollment open
    |
    dexamethasone injection
    3ms
    MajesTEC-3: A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (clinicaltrials.gov)
    P3, N=587, Active, not recruiting, Janssen Research & Development, LLC | Trial completion date: Oct 2026 --> Dec 2028
    Trial completion date • Combination therapy
    |
    bortezomib • pomalidomide • Darzalex Faspro (daratumumab/hyaluronidase) • Tecvayli (teclistamab-cqyv) • dexamethasone injection
    3ms
    Dexamethasone for Post Traumatic Headache (clinicaltrials.gov)
    P4, N=162, Recruiting, Montefiore Medical Center | Trial completion date: Feb 2024 --> Oct 2024 | Trial primary completion date: Jan 2024 --> Sep 2024
    Trial completion date • Trial primary completion date
    |
    dexamethasone injection
    3ms
    Comparative study of dexamethasone premedication regimens with docetaxel chemotherapy in early HER-2 positive breast cancer: A safety net hospital experience. (PubMed, J Oncol Pharm Pract)
    A single dose of intravenous dexamethasone alone or followed by lower doses of oral dexamethasone may improve patient compliance and avoid delays in chemotherapy, without an increase in docetaxel toxicity.
    Journal
    |
    HER-2 (Human epidermal growth factor receptor 2)
    |
    HER-2 positive
    |
    docetaxel • dexamethasone injection
    3ms
    PAODEX: The Effect of Perioperative Dexamethasone Administration on Postoperative Pain in Patients Undergoing Periacetabular Osteotomy. (clinicaltrials.gov)
    P2/3, N=90, Completed, Odense University Hospital | Active, not recruiting --> Completed
    Trial completion
    |
    IL6 (Interleukin 6) • TNFA (Tumor Necrosis Factor-Alpha) • IL10 (Interleukin 10) • CRP (C-reactive protein)
    |
    dexamethasone injection
    3ms
    Oral Dexamethasone for Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy (clinicaltrials.gov)
    P3, N=814, Not yet recruiting, Mansoura University
    New P3 trial
    |
    dexamethasone injection