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    GENE:

    DDX43 (DEAD-Box Helicase 43)

    i
    Other names: DDX43, DEAD-Box Helicase 43 , Cancer/Testis Antigen 13, Probable ATP-Dependent RNA Helicase DDX43, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 43 , DEAD Box Protein HAGE , Helical Antigen, CT13 , HAGE , DEAD-Box Protein 43 , DEAD Box Protein 43
    over1year
    Effect of DNMT3A R882H Hot Spot Mutations on DDX43 Promoter Methylation in Acute Myeloid Leukemia. (PubMed, Biomed Res Int)
    The DNMT3A R882H mutation is typically present in a minority of AML patients. Nevertheless, this mutation is associated with a reduced frequency of methylation in the DDX43 promoter region.
    Journal
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    DNMT3A (DNA methyltransferase 1) • DDX43 (DEAD-Box Helicase 43)
    almost3years
    DDX43 mRNA expression and protein levels in relation to clinicopathological profile of breast cancer. (PubMed, PLoS One)
    This study explored the potential of using blood DDX43 mRNA expression or protein levels, or both in clinical settings as a marker of disease progression in human breast cancer. DDX43 mRNA expression proposes a less invasive method for discriminating benign from malignant BC.
    Journal
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    DDX43 (DEAD-Box Helicase 43)
    over4years
    A Novel HAGE/WT1-ImmunoBody Vaccine Combination Enhances Anti-Tumour Responses When Compared to Either Vaccine Alone. (PubMed, Front Oncol)
    Overall, this work demonstrates that combining both HAGE- and WT1-ImmunoBody into a single vaccine is better than either vaccine alone. This combination vaccine could be given to patients whose cancer expresses HAGE and WT1 in parallel with existing therapies in order to decrease the chance of disease progression and relapse.
    Journal
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    IFNG (Interferon, gamma) • WT1 (WT1 Transcription Factor) • DDX43 (DEAD-Box Helicase 43)