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    BIOMARKER:

    CTNNA1 deletion

    i
    Other names: CTNNA1, Catenin Alpha 1, Renal Carcinoma Antigen NY-REN-13, Catenin Alpha-1, Alpha-E-Catenin, Catenin (Cadherin-Associated Protein), Alpha 1, 102kDa, Catenin (Cadherin-Associated Protein), Alpha 1 (102kD), Epididymis Secretory Sperm Binding Protein, Cadherin-Associated Protein, Alpha E-Catenin, CAP102, MDPT2
    Entrez ID:
    1495
    Related biomarkers:
    Others
    8ms
    Frequency of CDH1, CTNNA1 and CTNND1 Germline Variants in Families with Diffuse and Mixed Gastric Cancer. (PubMed, Cancers (Basel))
    We did not find any pathogenic CDH1, CTNNA1 or CTNND1 variant in index patients with early-onset/familial mixed gastric cancer, so there is no evidence that supports including this tumor type in the testing criteria for germline variants in these genes. The role of the CTNND1 gene in inherited gastric cancer predisposition is still unclear.
    Journal
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    CDH1 (Cadherin 1) • CTNNA1 (Catenin Alpha 1) • CTNND1 (Catenin Delta 1)
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    CDH1 deletion • CTNNA1 deletion