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    BIOMARKER:

    CTGF positive

    i
    Other names: CTGF, CCN2, IGFBP8, Connective tissue growth factor
    Entrez ID:
    1490
    Associations

    News

    Trials
    over3years
    STAT3 is Activated by CTGF-mediated Tumor-stroma Cross Talk to Promote HCC Progression. (PubMed, Cell Mol Gastroenterol Hepatol)
    STAT3 is activated by CTGF-mediated tumor-stroma crosstalk to promote HCC progression. STAT3-CTGF positive feedback loop could be a therapeutic target.
    Journal
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    KRAS (KRAS proto-oncogene GTPase) • IL6 (Interleukin 6) • STAT3 (Signal Transducer And Activator Of Transcription 3) • CTGF (Connective tissue growth factor)
    |
    KRAS mutation • KRAS G13 • IL6 expression • CTGF positive