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    BIOMARKER:

    CSF3R M696T

    i
    Other names: CSF3R, Colony Stimulating Factor 3 Receptor, Colony Stimulating Factor 3 Receptor (Granulocyte), Granulocyte Colony-Stimulating Factor Receptor, G-CSF Receptor, CD114 Antigen, G-CSF-R, GCSFR, CD114, SCN7
    Entrez ID:
    1441
    Related biomarkers:
    Mutation
    Others
    over2years
    Colony-stimulating factor 3 receptor (CSF3R) M696T mutation does not impact on clinical outcomes of a Ph+ acute lymphoblastic leukemia patient. (PubMed, Blood Sci)
    The in vitro experiment results showed that the CSF3R M696T mutation contributes marginally to the tumor transformation of Ba/F3 cells, indicating that CSF3R M696T mutation was neutral in tumor transformation ability. We concluded that TKI is effective in patients with the CSF3R M696T mutation in Ph ALL and donors with CSF3R M696T mutation might still be selected as the candidate for transplantation.
    Clinical data • Journal
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    CSF3R (Colony Stimulating Factor 3 Receptor)
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    CSF3R T618I • CSF3R M696T