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GENE:

CRYBA4 (Crystallin Beta A4)

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Other names: CRYBA4, Crystallin Beta A4, Beta-Crystallin A4, Beta-A4 Crystallin, Beta Crystallin A4 Chain Transcript PS, Crystallin, Beta Polypeptide A4, Beta Crystallin Alpha 4 Chain, Eye Lens Structural Protein, Crystallin, Beta A4, CTRCT23, MCOPCT4, CYRBA4
Associations
Trials
over3years
The Involvement of Insulin-Like Growth Factor 2 Messenger Ribonucleic Acid-Binding Protein 2 in the Regulation of the Expression of Breast Cancer-Related Genes. (PubMed, Breast Cancer (Dove Med Press))
Compared with the control group, the IGF2BP2 overexpression group had significantly increased expressions of IFIT2, CCL20, and CXCL10 (P < 0.05). IGF2BP2 may promote the invasion and proliferation of human breast cancer cells by up-regulating breast cancer-related genes, such as IFIT2, CCL20, and CXCL10.
Journal • IO biomarker
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TNFA (Tumor Necrosis Factor-Alpha) • CXCL10 (Chemokine (C-X-C motif) ligand 10) • CCL20 (C-C Motif Chemokine Ligand 20) • IGF2 (Insulin-like growth factor 2) • CRYBA4 (Crystallin Beta A4) • IFIT2 (Interferon Induced Protein With Tetratricopeptide Repeats 2) • IGF2BP2 (Insulin Like Growth Factor 2 MRNA Binding Protein 2)