CRP (C-reactive protein)

The integration of CRAFITY score, radiomics, and deep learning features contributed to predicting PFS for patients with HCC undergoing IMT-MTT-TACE. This combined model holds promise for enabling precise pretreatment risk stratification and optimizing monitoring protocols, thereby guiding prognosis assessment and individualized clinical treatment decisions.

In this pediatric cohort of cr-FMF patients, both anakinra and canakinumab were effective in reducing disease activity and inflammation. Anakinra offered rapid symptom relief but had frequent injection site reactions. Canakinumab provided sustained control with fewer local side effects but required monitoring for rare complications.

P=N/A, N=131, Completed, Ankara Etlik City Hospital | Active, not recruiting --> Completed

The machine learning model incorporating LCR and TNM staging is a robust tool for predicting postoperative survival following radical resection for GBC.

NAM is getting attention for its crucial and cost-effective role in preventing the adverse effects of gamma irradiation, this might encourage the use of NAM as a radio-protective agent on a potentially large scale.

P2, N=450, Not yet recruiting, Changchun GeneScience Pharmaceutical Co., Ltd.

Upadacitinib is an effective induction and maintenance therapy for refractory pediatric UC and IBD-U. Effectiveness should be weighed against the potential risks of AEs.

Patients admitted for IRAEs tended to have high-grade toxicity and high mortality rates, highlighting the need for timely diagnostics and treatment. A cytokine signature of elevated CRP, CD25, IL-10, and IL-6 was identified and associated with IRAEs.

These findings highlight the value of integrating data from different diseases (lymphoma) to improve predictions in a target disease (CLL), and represent a step toward data-driven identification of CLL patients at high risk of infection during treatment.

AST treatment mitigated these fibrotic changes, as evidenced by reductions in gene expression (p=0.001 for COL1A1 and p=0.005 for COL3A1) and improvements in Masson's trichrome staining. In conclusion, this study suggests that AST may confer a protective effect against BPA-induced testicular damage by reducing apoptosis and fibrosis; however, changes in oxidative stress markers did not achieve statistical significance. Furthermore, AST may enhance spermatogenesis.

Combined serum MCP-1 and hs-CRP levels could predict all-cause and cause-specific mortality rates in the general population.

MCO membranes provide clearance of middle-sized uremic toxins. This effect is most prominent for β2-microglobulin and does not differ between the two MCO dialyzers studied. MCO membranes may cause some albumin loss, and heparin requirements may increase during their use.