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    DRUG:

    Compound E

    i
    Other names: Compound E, γ-secretase inhibitor XXI, gamma-secretase inhibitor XXI, GSI-XXI
    Company:
    Beijing Normal University, Southeast University, University of Brescia Medical School
    Drug class:
    γ-secretase inhibitor
    Related drugs:
    10ms
    Evidence-based identification of breast cancer and associated ovarian and uterus cancer risk components in source waters from high incidence area in the Pearl River Basin, China. (PubMed, Sci Total Environ)
    Moreover, these identified water components were present at levels comparable to other regions with high female cancer prevalence, suggesting that the potential risk of these components may not be exclusive to the study region. Together, multiple levels of evidence suggested that long-term co-exposures to source water estrogenic components may be important to the development of breast, ovarian, and uterus cancers.
    Journal
    |
    ER (Estrogen receptor)
    |
    Compound E