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    DRUG:

    KUR-501

    i
    Other names: KUR-501, CMD-501, CAR-NKT therapy, CAR.GD2-IL-15 NKTs, Chimeric antigen receptors natural killer T-cells (CAR-NKT) therapy, GINAKIT cells, GD2-CAR, GD2-CAR NKT cells, CAR-modified NKT-cell therapy
    Associations

    News

    Trials
    Company:
    Athenex, Baylor College of Medicine, Texas Children’s Hospital
    Drug class:
    GD2 ganglioside inhibitor
    Related drugs:
    Associations

    News

    Trials
    11ms
    Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results. (PubMed, Nat Med)
    No dose-limiting toxicities occurred; one patient experienced grade 2 cytokine release syndrome that was resolved by tocilizumab. Additionally, their anti-tumor activity may be enhanced by targeting BTG1. ClinicalTrials.gov registration: NCT03294954 .
    P1 data • Journal
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    IL15 (Interleukin 15)
    |
    Actemra IV (tocilizumab) • KUR-501