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    GENE:

    CLCA2 (Chloride Channel Accessory 2)

    i
    Other names: CLCA2, Chloride Channel Accessory 2, CLCRG2, Chloride Channel, Calcium Activated, Family Member 2, Calcium-Activated Chloride Channel Regulator 2, Calcium-Activated Chloride Channel Protein 3, CaCC-3, CACC3, Calcium-Activated Chloride Channel Family Member 2, CLCA Family Member 2, Chloride Channel Regulator, Chloride Channel Regulator 2, HCaCC-3, HCLCA2, CACC
    Associations

    News

    Trials
    over1year
    Expression of Survivin, CK7, ASH1, HMGB3, L587S, and CLCA2 in Peripheral Blood of Lung Cancer Patients by Real-Time Polymerase Chain Reaction. (PubMed, Cureus)
    Conclusions Lifestyle and geographical variation might be a probable cause of variable gene expression as compared to other studies. However, further research is needed to determine the clinical implication of these markers, especially in larger groups of early-stage patients.
    Journal • Polymerase Chain Reaction
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    BIRC5 (Baculoviral IAP repeat containing 5) • CLCA2 (Chloride Channel Accessory 2)
    over3years
    CLCA2 overexpression suppresses epithelial-to-mesenchymal transition in cervical cancer cells through inactivation of ERK/JNK/p38-MAPK signaling pathways. (PubMed, BMC Mol Cell Biol)
    In conclusion, overexpression of CLCA2 inhibited the progression of cervical cancer in vivo and in vitro. This may provide a theoretical basis for CLCA2 as a new indicator of clinical diagnosis and prognosis of cervical cancer or as a potential target of drug therapy.
    Journal
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    CLCA2 (Chloride Channel Accessory 2)