^
    Contact us  to learn more about
    our Premium Content:  News alerts, weekly reports and conference planners
    BIOMARKER:

    CDCA3 overexpression

    i
    Other names: Cell Division Cycle Associated 3, TOME-1, GRCC8, Cell Division Cycle-Associated Protein 3, Trigger Of Mitotic Entry Protein 1, Gene-Rich Cluster Protein C8, Trigger Of Mitotic Entry 1, CDCA3, TOME1, C8
    Entrez ID:
    83461
    Related biomarkers:
    Others
    8ms
    Prognostic value of cell division cycle-associated protein-3 in prostate cancer. (PubMed, Medicine (Baltimore))
    CDCA3 is significantly associated with the prognosis of PCa, which may be an indicator of the diagnosis and prognosis of PCa and a new therapeutic target.
    Journal
    |
    CDCA3 (Cell Division Cycle Associated 3) • CCNA2 (Cyclin A2) • CCNB2 (Cyclin B2) • CDC20 (Cell Division Cycle 20) • CDK1 (Cyclin-dependent kinase 1) • BUB1 (BUB1 Mitotic Checkpoint Serine/Threonine Kinase)
    |
    CDCA3 overexpression
    10ms
    Curcumin targets miR-134-5p to suppress the progression of colorectal cancer through regulating the CDCA3/CDK1 pathway. (PubMed, Naunyn Schmiedebergs Arch Pharmacol)
    In addition, curcumin treatment repressed tumor growth in colorectal cancer via increasing miR-134-5p and downregulating CDCA3 and CDK1 expression in vivo. Our findings provided the evidence that curcumin upregulated miR-134-5p to inhibit the progression of colorectal cancer by regulating CDCA3/CDK1 pathway.
    Journal
    |
    MYC (V-myc avian myelocytomatosis viral oncogene homolog) • CDCA3 (Cell Division Cycle Associated 3) • MMP9 (Matrix metallopeptidase 9) • CDK1 (Cyclin-dependent kinase 1)
    |
    CDCA3 overexpression • CDK1 overexpression
    2years
    Prognostic value of CDCA3 in kidney renal papillary cell carcinoma. (PubMed, Aging (Albany NY))
    Our results indicated that high CDCA3 mRNA expression is significantly associated with some clinicopathologic parameters in KIRP patients High CDCA3 mRNA expression associated with a shorter overall survival, progression-free interval, and disease-special survival. Taken together, CDCA3 is a potential target for the development of anti-KIRP therapeutics and is an efficient prognostic marker.
    Journal
    |
    CDCA3 (Cell Division Cycle Associated 3)
    |
    CDCA3 overexpression