CD5 positive

She was treated with intrathecal chemotherapy with improvement in symptoms and resolution of ophthalmoplegia but was left with residual anisocoria and mild ptosis. This presentation (concomitant Horner and ipsilateral ONP) is rare and typically localises to the ipsilateral cavernous sinus, which appeared radiologically normal in this case.

Indeed, no structural variations or copy number alterations involving PD-1 ligands were detected by targeted-capture sequencing and fluorescence in situ hybridization. While further studies are warranted, we may have confirmed similarity between PCNS-LBCLs and intravascular large B-cell lymphomas from a molecular standpoint.

With prompt diagnosis, intervention and intensive monitoring, the end-organ damage was successfully prevented. This case report highlights the importance of keeping high index of suspicion for STLS even without a background history of malignancy as this life-threatening condition is potentially salvageable.

P1, N=19, Terminated, Beijing Boren Hospital | Recruiting --> Terminated; ethic commitee decision

P1, N=0, Withdrawn, Beijing Boren Hospital | N=18 --> 0 | Trial completion date: Jul 2024 --> Dec 2023 | Recruiting --> Withdrawn | Trial primary completion date: Jul 2024 --> Dec 2023

The lymphoma and EN developed simultaneously and followed a parallel clinical course after chemotherapy, suggesting that EN was a paraneoplastic symptom of CD5+ DLBCL. Recognizing and treating underlying malignancies in patients presenting with EN is crucial.

P2, N=39, Recruiting, Sun Yat-sen University

Moreover, the prognostic markers and treatment recommendations based on predictive markers are limited. This review aims to investigate some miRNAs that are dysregulated and possibly involved in CLL pathogenesis as a starting point for the proposal of new prognostic and predictive markers and, as more agents targeting miRNA expression become available, their potential role as therapeutic targets.

Lymphoma associated with thrombophilia is a rare presentation and not many cases have been reported in the literature. We present this case here on account of the rarity of lymphoma involving the appendix with associated thrombophilia.

LC-MBL is associated with an approximately two-fold increased risk of melanoma overall and a 2.74-fold increased risk of melanoma in situ.

P3, N=202, Completed, University of Ulm | Active, not recruiting --> Completed

Carcinoma showing thymus-like elements has recently been reported in the salivary gland. Similar to thymic carcinoma, tumor cells are positive for CD5 and are accompanied by T lymphocytes.