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    BIOMARKER:

    CCR7 overexpression

    i
    Other names: CCR7, BLR2, CD197, CDw197, CMKBR7, EBI1, Chemokine (C-C motif) receptor 7
    Entrez ID:
    1236
    Related biomarkers:
    Expression
    2ms
    Chemotherapy-induced cellular senescence promotes stemness of aggressive B-cell non-Hodgkin's lymphoma via CCR7/ARHGAP18/IKBα signaling activation. (PubMed, J Immunother Cancer)
    Together, TIS promotes the stemness of B-NHL cells via CCR7/ARHGAP18/IKBα signaling activation and targeting CCR7/ARHGAP18 might overcome the chemoresistance of senescent B-NHL cells by inhibiting stemness acquisition and maintenance.
    Journal
    |
    RHOA (Ras homolog family member A) • CCR7 (Chemokine (C-C motif) receptor 7) • ARHGAP • CCL21 (C-C Motif Chemokine Ligand 21)
    |
    CCR7 overexpression • CCR7 expresion
    |
    doxorubicin hydrochloride
    10ms
    Chemokine receptor 7 contributes to T- and B-cell filtering in ageing bladder, cystitis and bladder cancer. (PubMed, Immun Ageing)
    In this study, we characterised the expression profiles of immune cells in bladder tissues of aged and young mice and demonstrated that CCR7-mediated T- and B-cell filtration contributes to the development of bladder ageing, IC/BPS and BLCA.
    Journal
    |
    CCR7 (Chemokine (C-C motif) receptor 7)
    |
    CCR7 overexpression • CCR7 expresion