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BIOMARKER:

CCNA2 overexpression

i
Other names: CCNA2, CCN1, CCNA, Cyclin A2
Entrez ID:
Related biomarkers:
6ms
E2F1 transcriptionally regulates CCNA2 expression to promote triple negative breast cancer tumorigenicity. (PubMed, Cancer Biomark)
Our data indicate that E2F1 promotes TNBC proliferation and invasion by upregulating CCNA2 expression. E2F1 and CCNA2 are potential candidates that may be targeted for effective TNBC treatment.
Journal
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CCNA2 (Cyclin A2) • E2F1 (E2F transcription factor 1)
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CCNA2 expression • CCNA2 overexpression
7ms
Integrative analysis of key candidate genes and signaling pathways in ovarian cancer by bioinformatics. (PubMed, J Ovarian Res)
Taken together, our study provided evidence concerning the altered expression of genes in ovarian cancer tissues compared with normal tissues. In vivo and in vitro experiments are required to verify the results of the present study.
Journal
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TOP2A (DNA topoisomerase 2-alpha) • CCNA2 (Cyclin A2) • CDC20 (Cell Division Cycle 20) • CDK1 (Cyclin-dependent kinase 1) • KIF11 (Kinesin Family Member 11) • BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) • CCNB1 (Cyclin B1) • CDCA8 (Cell Division Cycle Associated 8)
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CCNA2 expression • CCNA2 overexpression
7ms
In silico analysis of differentially expressed genesets in metastatic breast cancer identifies potential prognostic biomarkers. (PubMed, World J Surg Oncol)
Transcriptome datasets of metastatic breast cancer obtained from Oncomine allow the identification of metastatic breast cancer-specific biological functions, pathways, and novel biomarkers to predict clinical outcomes of breast cancer patients. Further functional studies are needed to warrant validation of their roles as functional tumor-promoting or tumor-suppressing genes.
Journal
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EGFR (Epidermal growth factor receptor) • CCNA2 (Cyclin A2) • LRIG1 (Leucine Rich Repeats And Immunoglobulin Like Domains 1)
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CCNA2 expression • CCNA2 overexpression