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    BIOMARKER:

    CCDC85A-ALK fusion

    i
    Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor, CCDC85A, Coiled-Coil Domain Containing 85A, KIAA1912, Coiled-Coil Domain-Containing Protein 85A
    Entrez ID:
    238; 114800
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    over1year
    Lung adenocarcinoma with an uncommon CCDC85A-ALK fusion responding to alectinib: A case report. (PubMed, J Cell Mol Med)
    This is the first report of a lung adenocarcinoma patient harbouring a new uncommon anaplastic lymphocyte kinase fusion that showed a remarkable response to alectinib. NGS aids in selecting treatment in non-small cell lung cancer patients.
    Journal
    |
    CCDC85A (Coiled-Coil Domain Containing 85A)
    |
    ALK fusion • CCDC85A-ALK fusion
    |
    Alecensa (alectinib)