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DRUG:

CAR.B7-H3 T

i
Other names: CAR.B7-H3 T, CAR.B7-H3T, Chimeric antigen receptor T cells with B7.H3 molecular target, Autologous CAR-T Cells Targeting B7-H3
Associations
Company:
UNC Lineberger Comprehensive Cancer Center
Drug class:
B7-H3-targeted CAR-T immunotherapy
Associations
1m
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc (clinicaltrials.gov)
P1, N=36, Recruiting, UNC Lineberger Comprehensive Cancer Center | Trial primary completion date: Oct 2024 --> May 2030
Trial primary completion date • CAR T-Cell Therapy
|
CD276 (CD276 Molecule)
|
CAR.B7-H3 T
3ms
Autologous CAR-T Cells Targeting B7-H3 in PDAC (clinicaltrials.gov)
P1, N=27, Recruiting, UNC Lineberger Comprehensive Cancer Center | Not yet recruiting --> Recruiting
Enrollment open • CAR T-Cell Therapy
|
CD276 (CD276 Molecule)
|
CAR.B7-H3 T
3ms
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells (clinicaltrials.gov)
P1, N=27, Recruiting, UNC Lineberger Comprehensive Cancer Center | Not yet recruiting --> Recruiting
Enrollment open • CAR T-Cell Therapy
|
cyclophosphamide • fludarabine IV • CAR.B7-H3 T
4ms
Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells (clinicaltrials.gov)
P1, N=42, Recruiting, UNC Lineberger Comprehensive Cancer Center | Not yet recruiting --> Recruiting
Enrollment open • CAR T-Cell Therapy
|
cyclophosphamide • fludarabine IV • CAR.B7-H3 T
4ms
Autologous CAR-T Cells Targeting B7-H3 in PDAC (clinicaltrials.gov)
P1, N=27, Not yet recruiting, UNC Lineberger Comprehensive Cancer Center | Initiation date: Jun 2024 --> Sep 2024
Trial initiation date • CAR T-Cell Therapy
|
CD276 (CD276 Molecule)
|
CAR.B7-H3 T
7ms
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells (clinicaltrials.gov)
P1, N=27, Not yet recruiting, UNC Lineberger Comprehensive Cancer Center | Initiation date: Mar 2024 --> Jul 2024
Trial initiation date • CAR T-Cell Therapy
|
cyclophosphamide • fludarabine IV • CAR.B7-H3 T
7ms
Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells (clinicaltrials.gov)
P1, N=42, Not yet recruiting, UNC Lineberger Comprehensive Cancer Center
New P1 trial
|
cyclophosphamide • fludarabine IV • CAR.B7-H3 T
8ms
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells (clinicaltrials.gov)
P1, N=27, Not yet recruiting, UNC Lineberger Comprehensive Cancer Center
New P1 trial • CAR T-Cell Therapy
|
cyclophosphamide • fludarabine IV • CAR.B7-H3 T
11ms
Autologous CAR-T Cells Targeting B7-H3 in PDAC (clinicaltrials.gov)
P1, N=27, Not yet recruiting, UNC Lineberger Comprehensive Cancer Center
New P1 trial • CAR T-Cell Therapy
|
CD276 (CD276 Molecule)
|
CAR.B7-H3 T
2years
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc (clinicaltrials.gov)
P1, N=36, Recruiting, UNC Lineberger Comprehensive Cancer Center | Not yet recruiting --> Recruiting | Trial primary completion date: May 2030 --> Oct 2024
Enrollment open • Trial primary completion date • CAR T-Cell Therapy
|
CD276 (CD276 Molecule)
|
CAR.B7-H3 T
over2years
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc (clinicaltrials.gov)
P1, N=36, Not yet recruiting, UNC Lineberger Comprehensive Cancer Center
New P1 trial • CAR T-Cell Therapy
|
CD276 (CD276 Molecule)
|
CAR.B7-H3 T