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DRUG:

Cantrixil (TRX-E-002-1)

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Other names: TRXE-002, TRXE-002-1, TRXE002, TRX-E-002-1, TRXE-002-1 encapsulated in a cyclodextrin envelope, TRX1, TRXE 002 1, TRX E 002 1
Associations
Company:
Kazia, Vivesto, Yale University
Drug class:
Cell death stimulant
Associations
over5years
[VIRTUAL] TRX-E-002-1 in treatment-refractory ovarian cancer - 3-month follow-up results from a phase I study dose escalation phase (AACR-II 2020)
IP administered TRX-E-002-1 as a first-in-class, dual acting, anti-cancer therapy has preliminary activity for the treatment of platinum resistant ovarian cancer for patients who have demonstrated resistance to a range of prior treatments.
P1 data • PARP Biomarker
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CD44 (CD44 Molecule)
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Cantrixil (TRX-E-002-1)
over5years
Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer. (clinicaltrials.gov)
P1, N=28, Completed, Kazia Therapeutics Limited | Active, not recruiting --> Completed | Trial primary completion date: Dec 2019 --> Mar 2020
Clinical • Trial completion • Trial primary completion date
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BRCA (Breast cancer early onset)
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Cantrixil (TRX-E-002-1)