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GENE:

CA 19-9 (Cancer antigen 19-9)

i
Other names: CA 19-9, Cancer antigen 19-9
Associations
2d
Iodine-125 Brachytherapy Combined with Biliary Stenting in Advanced Pancreatic Cancer: A Clinical Application Study. (PubMed, Acad Radiol)
Biliary stent combined with iodine-125 intraluminal brachytherapy significantly prolonged SPT compared to stent-alone in patients with advanced pancreatic cancer complicated by obstructive jaundice, although it did not significantly improve survival outcomes. Higher ECOG performance score and higher CA19-9 level after jaundice reduce were associated with poor prognosis.
Journal
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CA 19-9 (Cancer antigen 19-9)
3d
Critical Perioperative Factors Influencing Postoperative Complications and Long-Term Survival in Patients with Gastric Cancer. (PubMed, JSLS)
The PNI, LVI, TNM stage, ALB, CA19-9, age, and CEA were identified as independent perioperative risk factors for long-term survival in gastric cancer patients undergoing gastrectomy. The PNI is an independent factor influencing both short-term complications and long-term survival.
Retrospective data • Journal
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CEACAM5 (CEA Cell Adhesion Molecule 5) • AFP (Alpha-fetoprotein) • CA 19-9 (Cancer antigen 19-9)
3d
Graphene-enabled QBIC terahertz metamaterial biosensor for pancreatic cancer biomarker detection. (PubMed, Opt Express)
Under ambient conditions (25 °C, 4% relative humidity), the device shows highly repeatable measurement performance. This work provides a label-free, rapid, and non-destructive terahertz sensing platform with strong potential for biosensing and biochemical monitoring.
Journal
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CA 19-9 (Cancer antigen 19-9)
4d
A Curious Case of Intraductal Papillary Mucinous Neoplasm of the Bile Duct Presenting With Cholangitis. (PubMed, Cureus)
Physicians need to be aware of such cases, as their management is different from cholangitis due to other causes, which are frequently encountered in clinical practice. IPMN-B requires a detailed imaging workup and definitive surgical resection due to its high risk of malignant transformation.
Journal
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CA 19-9 (Cancer antigen 19-9)
5d
Clinical Trial of WBC100 on Advanced Solid Tumor (clinicaltrials.gov)
P1, N=68, Terminated, Zhejiang University | Recruiting --> Terminated; sponsor's decision to change development strategy (the QOD cohort was completed).
Trial termination
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MYC (V-myc avian myelocytomatosis viral oncogene homolog) • CA 19-9 (Cancer antigen 19-9)
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WB100
7d
Computed tomography with carcinoembryonic antigen and carbohydrate antigen 19-9 in diagnosing lymph node metastasis of early gastric cancer. (PubMed, World J Gastrointest Oncol)
The combination of CT with CEA or CA19-9 improves sensitivity for detecting LNM in EGC, supporting personalized treatment planning and demonstrating clinical value.
Journal
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CEACAM5 (CEA Cell Adhesion Molecule 5) • CA 19-9 (Cancer antigen 19-9)
7d
Efficacy and safety of integrated Chinese and Western medicine in advanced pancreatic cancer: A double-center retrospective cohort study. (PubMed, World J Gastrointest Oncol)
ICWM extended survival in patients with advanced PC, improved long-term efficacy, controlled local lesions, reduced serum tumor markers, enhanced immune function, and improved short-term outcomes, with a favorable safety profile.
Retrospective data • Journal
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CD8 (cluster of differentiation 8) • CD4 (CD4 Molecule) • CA 19-9 (Cancer antigen 19-9)
7d
Timeliness of postoperative serum carcinoembryonic antigen monitoring for predicting recurrence after gastric cancer surgery. (PubMed, World J Gastrointest Surg)
Dynamic postoperative monitoring of serum CEA and AFP enables early prediction and detection of gastric cancer recurrence.
Journal
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CEACAM5 (CEA Cell Adhesion Molecule 5) • AFP (Alpha-fetoprotein) • CA 19-9 (Cancer antigen 19-9)
7d
Efficacy and safety of cinobufacini capsules combined with oxaliplatin-based chemotherapy for advanced colorectal cancer: a human systematic review and meta-analysis. (PubMed, Front Pharmacol)
Cinobufacini combined with oxaliplatin-based chemotherapy may enhance short-term efficacy, immune function, and safety in advanced CRC. However, due to limitations of existing RCTs, these findings should be interpreted cautiously, and further large-scale, high-quality trials are required.
Retrospective data • Review • Journal
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CEACAM5 (CEA Cell Adhesion Molecule 5) • CD4 (CD4 Molecule) • CA 19-9 (Cancer antigen 19-9)
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oxaliplatin
9d
PanMETAI - a high performance tabular foundation model for accurate pancreatic cancer diagnosis via NMR metabolomics. (PubMed, Nat Commun)
Notably, it identifies key signature patterns that improve early-stage (I/II) PDAC diagnosis and perform well with small sample sizes (n = 50). TabPFN-PanMETAI offers a rapid, accurate, and non-invasive tool for early PDAC detection, with strong potential for clinical application.
Journal • Metabolomic study
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CA 19-9 (Cancer antigen 19-9)
9d
Utilizing machine learning and SHAP analysis to develop a prognostic survival prediction model for gastric cancer patients following radical gastrectomy (PubMed, Zhonghua Wei Chang Wai Ke Za Zhi)
Tumor T stage, extent of resection, age, CEA, CA199, gender, tumor longest diameter, and differentiation degree are associated with OS after radical gastrectomy. This study constructed an SVM-based prediction model with good precision and developed a corresponding website.
Retrospective data • Journal
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CEACAM5 (CEA Cell Adhesion Molecule 5) • CA 19-9 (Cancer antigen 19-9)
9d
New P2 trial
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HER-2 (Human epidermal growth factor receptor 2) • CA 19-9 (Cancer antigen 19-9)
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HER-2 overexpression • HER-2 amplification
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Avastin (bevacizumab) • Enhertu (fam-trastuzumab deruxtecan-nxki) • capecitabine