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DRUG:
BNT113
i
Other names:
BNT113, HPV FixVAC, Hare-40 FixVAC, RBLO 15.1(LIP)/RBLO 16.1(LIP), E6/E7 RNA(LIP), HPV mRNA vaccine, HPV anti-CD40 RNA vaccine, BNT 113, BNT-113
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News alerts, weekly reports and conference planners
Associations
News
Trials
Company:
BioNTech
Drug class:
HPV-16 E6 protein inhibitor, HPV-16 E7 protein inhibitor
Related drugs:
‹
Versamune HPV (1)
HB-200 (1)
CRTE7A2-01 (0)
HB-201 (0)
HPV-T (0)
ISA101 (0)
MEDI0457 (0)
NEXI-003 (0)
RTX-321 (0)
VGX-3100 (0)
TG4001 (0)
DPX-E7 (0)
E7 TCR-T (0)
KITE-439 (0)
axalimogene filolisbac (0)
TSC-200-A0201 (0)
Versamune HPV (1)
HB-200 (1)
CRTE7A2-01 (0)
HB-201 (0)
HPV-T (0)
ISA101 (0)
MEDI0457 (0)
NEXI-003 (0)
RTX-321 (0)
VGX-3100 (0)
TG4001 (0)
DPX-E7 (0)
E7 TCR-T (0)
KITE-439 (0)
axalimogene filolisbac (0)
TSC-200-A0201 (0)
›
Associations
News
Trials
Filter by
Latest
2ms
Observational study on the correlation between the immune response of patients' peripheral blood stimulated by therapeutic HPV mRNA vaccine in vitro and the pathological results and clinical prognosis of patients (ChiCTR2400087487)
P=N/A, N=150, Not yet recruiting, Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine; Renji Hospital affiliated to Shanghai Jiaotong University School of Medi
2 months ago
New trial
|
BNT113
10ms
HARE-40: HPV Anti-CD40 RNA vaccinE (clinicaltrials.gov)
P1/2, N=32, Completed, University of Southampton | Active, not recruiting --> Completed
10 months ago
Trial completion
|
BNT113
11ms
AHEAD-MERIT: A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (clinicaltrials.gov)
P2, N=285, Recruiting, BioNTech SE
11 months ago
Trial completion date • Trial primary completion date • Combination therapy • Metastases
|
PD-L1 (Programmed death ligand 1)
|
Keytruda (pembrolizumab) • BNT113
2years
AHEAD-MERIT: A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (clinicaltrials.gov)
P2; Trial completion date: May 2025 --> May 2028 | Trial primary completion date: May 2025 --> May 2028
2 years ago
Combination therapy • Trial completion date • Trial primary completion date
|
PD-L1 (Programmed death ligand 1)
|
PD-L1 expression
|
PD-L1 IHC 22C3 pharmDx
|
Keytruda (pembrolizumab) • BNT113
over3years
AHEAD-MERIT: A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (clinicaltrials.gov)
P2, N=285, Recruiting, BioNTech SE | Not yet recruiting --> Recruiting
over 3 years ago
Clinical • Enrollment open • Combination therapy
|
PD-L1 (Programmed death ligand 1)
|
PD-L1 expression
|
Keytruda (pembrolizumab) • BNT113
4years
AHEAD-MERIT: A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1 (clinicaltrials.gov)
P2, N=285, Not yet recruiting, BioNTech SE
4 years ago
Clinical • New P2 trial • Combination therapy
|
PD-L1 (Programmed death ligand 1)
|
PD-L1 expression
|
Keytruda (pembrolizumab) • BNT113
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