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    BIOMARKER:

    BCYRN1 overexpression

    i
    Other names: BCYRN1, Brain Cytoplasmic RNA 1, Brain Cytoplasmic RNA 1 (Non-Protein Coding), Long Intergenic Non-Protein Coding RNA 4, Brain Cytoplasmic RNA 200-Alpha, Non-Protein Coding RNA 4, NCRNA00004, LINC00004, BC200a, BCYRN1, BC200, Brain Cytoplasmic RNA 1 (Analog Of Mouse Bc1), Brain Cytoplasmic RNA 1 Bc1 Analog (Mouse) 2, Brain Cytoplasmic RNA 1 Bc1 Analog, NONHSAG027692.2, HSALNG0141597, BC200-Alpha, Lnc-EPCAM-8
    Entrez ID:
    618
    12ms
    Comprehensive analysis of prognostic value and immunotherapy prospect of brain cytoplasmic RNA1 in hepatocellular carcinoma. (PubMed, World J Gastrointest Oncol)
    Overexpression of BCYRN1 relates to poor prognosis and may be a potential prognostic factor and immunotherapeutic target in HCC.
    Journal • IO biomarker
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    BCYRN1 (Brain Cytoplasmic RNA 1)
    |
    BCYRN1 overexpression
    almost2years
    Long non-coding RNA brain cytoplasmic RNA 1 induces cisplatin-resistance of cervical cancer cells by sponging microRNA-330-5p and upregulating high-mobility group box 3. (PubMed, Gynecol Obstet Invest)
    BCYRN1 knockdown could disrupt DDP-resistance of CC cells through upregulating miR-330-5p to suppress HMGB3 mRNA level.
    Journal
    |
    BCYRN1 (Brain Cytoplasmic RNA 1)
    |
    BCYRN1 overexpression
    |
    cisplatin
    over3years
    LncRNA BCYRN1-induced autophagy enhances asparaginase resistance in extranodal NK/T-cell lymphoma. (PubMed, Theranostics)
    BCYRN1 could promote resistance to ASP by inducing autophagy, which could be reversed by inhibition of autophagy. Our findings highlight the feasibility of combining autophagy inhibition and ASP in the treatment of ENKTCL.
    Journal
    |
    BCYRN1 (Brain Cytoplasmic RNA 1)
    |
    BCYRN1 overexpression
    over3years
    LncRNA BCYRN1 inhibits glioma tumorigenesis by competitively binding with miR-619-5p to regulate CUEDC2 expression and the PTEN/AKT/p21 pathway. (PubMed, Oncogene)
    BCYRN1 functioned as a ceRNA to inhibit glioma progression by sponging miR-619-5p to regulate CUEDC2 expression and PTEN/AKT/p21 pathway. Our results indicated that BCYRN1 exerted tumor suppressor potential and might be a candidate in the diagnosis and treatment of glioma.
    Journal
    |
    BCYRN1 (Brain Cytoplasmic RNA 1)
    |
    PTEN expression • BCYRN1 overexpression