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    DRUG:

    AUTO6NG

    i
    Other names: AUTO6NG, AUTO6-NG, AUTO6 - Next Generation, AUTO6 NG
    Associations

    News

    Trials
    Company:
    Autolus, BioNTech
    Drug class:
    GD2-targeted CAR-T immunotherapy
    Related drugs:
    Associations

    News

    Trials
    1year
    Detection and quantification of integrated vector copy number by multiplex droplet digital PCR in dual-transduced CAR T cells. (PubMed, Mol Ther Methods Clin Dev)
    AUTO6NG is a dual-transduced GD2-targeting CAR that encodes distinct modules designed to enhance T cell activity in relapsed/refractory neuroblastoma...No differences were observed in measuring VCN between standard duplex and multiplex assays. Our results demonstrate that ddPCR is an accurate and cost-effective method for simultaneous detection of multiple targets in genomic DNA derived from engineered CAR T cells.
    Journal • CAR T-Cell Therapy
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    AUTO6NG