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DRUG:

AUTO6NG

i
Other names: AUTO6NG, AUTO6-NG, AUTO6 - Next Generation, AUTO6 NG
Associations
Trials
Company:
Autolus, BioNTech
Drug class:
GD2-targeted CAR-T immunotherapy
Associations
Trials
over1year
Detection and quantification of integrated vector copy number by multiplex droplet digital PCR in dual-transduced CAR T cells. (PubMed, Mol Ther Methods Clin Dev)
AUTO6NG is a dual-transduced GD2-targeting CAR that encodes distinct modules designed to enhance T cell activity in relapsed/refractory neuroblastoma...No differences were observed in measuring VCN between standard duplex and multiplex assays. Our results demonstrate that ddPCR is an accurate and cost-effective method for simultaneous detection of multiple targets in genomic DNA derived from engineered CAR T cells.
Journal • CAR T-Cell Therapy
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AUTO6NG