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GENE:

ASB16-AS1 (ASB16 Antisense RNA 1)

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Other names: ASB16-AS1, ASB16 Antisense RNA 1, C17orf65, DKFZp762C2414, Putative Uncharacterized Protein ASB16-AS1, Chromosome 17 Open Reading Frame 65, ASB16 Antisense Gene Protein 1, NONHSAG021911.2, NONHSAG021910.2, HSALNG0116707, HSALNG0116708, Lnc-ATXN7L3-3, CTB-175E5.4, ASB16-AS1
Associations
Trials
6ms
The Role of Epigenetic Biomarkers as Diagnostic, Predictive and Prognostic Factors in Colorectal Cancer. (PubMed, Cancers (Basel))
Selected lncRNAs, including THOR and LINC01094, have also demonstrated significant prognostic value. Despite these advances, challenges persist, including inconsistent reporting, limited external validation, and a lack of replication by independent research groups.
Review • Journal
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ERCC1 (Excision repair cross-complementation group 1) • MALAT1 (Metastasis associated lung adenocarcinoma transcript 1) • MIR21 (MicroRNA 21) • GAS6 (Growth arrest specific 6) • MIR211 (MicroRNA 211) • IGFBP3 (Insulin-like growth factor binding protein 3) • LINC01094 (Long Intergenic Non-Protein Coding RNA 1094) • MIR140 (MicroRNA 140) • MIR150 (MicroRNA 150) • MIR215 (MicroRNA 215) • MIR675 (MicroRNA 675) • SDC2 (Syndecan 2) • SEPTIN9 (Septin 9) • SNHG14 (Small Nucleolar RNA Host Gene 14) • ASB16-AS1 (ASB16 Antisense RNA 1)
over1year
In vivo delivery of PBAE/ZIF-8 enhances the sensitivity of colorectal cancer to doxorubicin through sh-LncRNA ASB16-AS1. (PubMed, J Biomater Sci Polym Ed)
LncRNA ASB16-AS1, miR-185-5p, and TEAD1 are involved in regulating cell viability, proliferation, and apoptosis, contributing to drug resistance in CRC cells. sh-LncRNA ASB16-AS1 enhances the sensitivity of CRC cells to DOX during treatment, and in vivo delivery of PZSNP may serve as an effective strategy to overcome chemotherapy resistance in CRC.
Preclinical • Journal
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miR-185 (MicroRNA 185) • TEAD1 (TEA Domain Transcription Factor 1) • ASB16-AS1 (ASB16 Antisense RNA 1)
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miR-185 expression
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doxorubicin hydrochloride
over2years
LncRNA ASB16-AS1 accelerates cellular process and chemoresistance of ovarian cancer cells by regulating GOLM1 expression via targeting miR-3918. (PubMed, Biochem Biophys Res Commun)
ASB16-AS1 facilitates the malignant processes and chemoresistance of OC cells via serving as miR-3918 sponge and positively modulating GOLM1 expression.
Journal
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GOLM1 (Golgi Membrane Protein 1) • ASB16-AS1 (ASB16 Antisense RNA 1) • MIR3918 (MicroRNA 3918)
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cisplatin